Tissue expression
Cell line expression
Protein structure
ZBTB7B
Zinc finger and BTB domain containing 7Bc-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B
This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Top validated antibodies |
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antibodies-online | ![]() |
3 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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OriGene | ![]() |
Monoclonal |
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GeneTex | ![]() |
Monoclonal |
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Biorbyt | ![]() |
Recombinant |
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