Tissue expression
Cell line expression
Protein structure
CCNF
Cyclin FFBX1, FBXO1
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA5-99463 | 1 references | Polyclonal |
WB
ICC
IHC
OA |
|
antibodies-online | ABIN2487036 | Polyclonal |
WB
ICC
IHC
|
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Affinity Biosciences | AF5357 | Polyclonal |
WB
EL
ICC
IHC |
||
Biorbyt | orb2243035 | Polyclonal |
WB
EL
ICC
IHC |
||
OriGene | AP06083PU-N | Polyclonal |
WB
EL
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider