Tissue expression
Cell line expression
Protein structure
TM2D1
TM2 domain containing 1BBP
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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Atlas Antibodies | HPA046058 | Polyclonal |
ICC
IHC |
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Invitrogen Antibodies | PA5-61139 | Polyclonal |
ICC
IHC |
||
LSBio | LS-B13636 | Polyclonal |
WB
IHC |
||
Novus Biologicals | NBP2-13436 | Polyclonal |
ICC
IHC |
||
Abbkine Scientific Co.Ltd. | ABP60706 | Polyclonal |
WB
EL |
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