Tissue expression
Cell line expression
Protein structure
PDIA3
Protein disulfide isomerase family A member 3ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016]
Top validated antibodies |
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Atlas Antibodies | HPA003230 | 4 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 15967-1-AP | 22 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | 15967-1-AP | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
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NovoPro Bioscience Inc. | 110374 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
||
antibodies-online | ABIN2484396 | 7 references | Monoclonal |
WB
ICC
IP
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider