Tissue expression
Cell line expression
Protein structure
NLRP7
NLR family pyrin domain containing 7CLR19.4, NALP7, NOD12, PAN7, PYPAF3
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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