Tissue expression
Cell line expression
Protein structure
CHD3
Chromodomain helicase DNA binding protein 3Mi-2a, Mi2-ALPHA, ZFH
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NBP1-51593 | 1 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
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antibodies-online | ABIN1106677 | 2 references | Monoclonal |
WB
ICC
IHC
FC |
|
OriGene | AM06458SU-N | Monoclonal |
WB
EL
ICC
IHC
FC
|
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GeneTex | GTX83232 | Monoclonal |
WB
EL
ICC
IHC
FC
|
||
Acris Antibodies GmbH | AM06458SU-N | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Supportive data in Antibodypedia
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Recommended by provider