Tissue expression
Cell line expression
Protein structure
FRMPD2
FERM and PDZ domain containing 2MGC35285, PDZD5C, PDZK5C
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]
Top validated antibodies |
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OriGene | ![]() |
1 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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