Tissue expression
Cell line expression
Protein structure
CLEC7A
C-type lectin domain containing 7ACD369, CLECSF12, dectin-1, hDectin-1, SCARE2
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX41467 | 3 references | Monoclonal |
WB
IP
IHC
FC
BN
|
|
Invitrogen Antibodies | PA5-34382 | 1 references | Polyclonal |
WB
ICC
IHC
OA |
|
R&D Systems | MAB1859 | 21 references | Monoclonal |
ICC
FC
BN
|
|
Novus Biologicals | MAB1859 | 22 references | Monoclonal |
ICC
FC
BN
|
|
antibodies-online | ABIN1449932 | 4 references | Polyclonal |
WB
EL
ICC
IHC |
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