Tissue expression
Cell line expression
Protein structure
RHOG
Ras homolog family member GARHG, MGC125835, MGC125836
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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Atlas Antibodies | HPA039871 | 1 references | Polyclonal |
WB
IHC |
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Affinity Biosciences | AF9182 | Polyclonal |
WB
EL
ICC
IHC |
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LSBio | LS-C467257 | Polyclonal |
WB
IHC |
||
Novus Biologicals | NBP1-88832 | 1 references | Polyclonal |
WB
IHC |
|
Invitrogen Antibodies | PA5-99704 | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider