Tissue expression
Cell line expression
Protein structure
DMAP1
DNA methyltransferase 1 associated protein 1DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 10411-1-AP | 6 references | Polyclonal |
WB
EL
IP
|
|
Invitrogen Antibodies | 10411-1-AP | Polyclonal |
WB
ICC
IP
OA |
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NovoPro Bioscience Inc. | 110001 | Polyclonal |
WB
EL
ICC
IP |
||
Cusabio Biotech Co., Ltd | CSB-PA873611LA01HU | Polyclonal |
WB
EL
ICC
IHC |
||
Abnova Corporation | H00055929-M01 | 1 references | Monoclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider