HOXC10

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation. [provided by RefSeq, Jul 2008]

Description

Homeobox C10

Tissue specificity

Tissue enriched (skeletal muscle)

Subcell location

Nucleoplasm, Nuclear bodies

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

12 (53985065 - 53990279)

Ensembl ID

ENSG00000180818  (ver. 103.38)

Orthologs

Mouse Hoxc10: ENSMUSG00000022484

UniProt

Q9NYD6

neXtProt

NX_Q9NYD6

Human splice variants
Mouse splice variants

Protein structure