Tissue expression
Cell line expression
Protein structure
ZBTB20
Zinc finger and BTB domain containing 20DKFZp566F123, DPZF, ODA-8S, ZNF288
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Top validated antibodies |
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Proteintech Group | ![]() |
3 references | Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Atlas Antibodies | ![]() |
2 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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