Tissue expression
Cell line expression
Protein structure
KLRC4
Killer cell lectin like receptor C4NKG2-F
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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LSBio | LS-C198544 | Monoclonal |
WB
EL |
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Invitrogen Antibodies | PA5-120301 | Polyclonal |
WB
ICC
IHC
|
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Biorbyt | orb184531 | Polyclonal |
EL
ICC
IHC
|
||
St John's Laboratory | STJ117007 | Polyclonal |
WB
ICC
IHC
|
||
antibodies-online | ABIN521837 | Monoclonal |
WB
EL |
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