PCBP3

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]

Description

Poly(rC) binding protein 3

Tissue specificity

Tissue enhanced (retina)

Subcell location

Nucleoplasm, Vesicles, Mitochondria

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

21 (45643694 - 45942454)

Ensembl ID

ENSG00000183570  (ver. 103.38)

Orthologs

Mouse Pcbp3: ENSMUSG00000001120

UniProt

P57721

neXtProt

NX_P57721

Human splice variants
Mouse splice variants

Protein structure