Tissue expression
Cell line expression
Protein structure
AP3M1
Adaptor related protein complex 3 subunit mu 1The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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Proteintech Group | 12114-1-AP | 2 references | Polyclonal |
WB
EL
IP
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GeneTex | GTX32019 | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP1-76589 | Polyclonal |
WB
EL
ICC
IHC |
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Boster Biological Technology | A12628 | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN2155898 | Polyclonal |
WB
EL
ICC
IHC |
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