Tissue expression
Cell line expression
Protein structure
FLRT2
Fibronectin leucine rich transmembrane protein 2This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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Biorbyt | orb2213075 | Polyclonal |
WB
ICC
IP
IHC |
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antibodies-online | ABIN4312171 | Polyclonal |
WB
IHC |
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GeneTex | GTX123309 | Polyclonal |
WB
IHC |
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Novus Biologicals | NBP2-43653 | Polyclonal |
WB
IHC |
||
Invitrogen Antibodies | PA5-32122 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider