Tissue expression
Cell line expression
Protein structure
PLCD1
Phospholipase C delta 1This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Top validated antibodies |
|||||
Invitrogen Antibodies | ![]() |
Polyclonal |
|
||
GeneTex | ![]() |
Polyclonal |
|
||
Novus Biologicals | ![]() |
Polyclonal |
|
||
antibodies-online | ![]() |
Polyclonal |
|
||
Santa Cruz Biotechnology | ![]() |
1 references | Polyclonal |
|