Tissue expression
Cell line expression
Protein structure
SPRY4
Sprouty RTK signaling antagonist 4This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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Proteintech Group | 22765-1-AP | 4 references | Polyclonal |
WB
EL
IHC
FC |
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Invitrogen Antibodies | PA5-31401 | 1 references | Polyclonal |
WB
IHC
OA
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|
NSJ Bioreagents | RQ5681 | Polyclonal |
WB
EL
IHC
FC |
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Boster Biological Technology | A04343-2 | Polyclonal |
WB
EL
IHC
FC |
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antibodies-online | ABIN2503543 | Polyclonal |
WB
ICC
IHC
FC |
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