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Protein structure
AGRN
AgrinAGRIN
This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Top validated antibodies |
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| R&D Systems |  AF550 |
2 references | Polyclonal |
WB
EL
IHC
BN
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| Boster Biological Technology | A04649 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | AF550 |
2 references | Polyclonal |
WB
IHC
BN
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| Biorbyt | orb623837 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Invitrogen Antibodies | PA5-112353 |
Polyclonal |
WB
EL
ICC
IHC
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