Tissue expression
Cell line expression
Protein structure
HSH2D
Hematopoietic SH2 domain containingALX, FLJ14886, HSH2
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]). [supplied by OMIM, Mar 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
Monoclonal |
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LSBio | ![]() |
Monoclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Abnova Corporation | ![]() |
Polyclonal |
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Everest Biotech | ![]() |
Polyclonal |
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