Tissue expression
Cell line expression
Protein structure

HLA-DQA1

Major histocompatibility complex, class II, DQ alpha 1
CELIAC1, HLA-DQA 
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]
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712 antibodies from 38 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
165 antibodies
Proteintech Group
1 antibody
antibodies-online
255 antibodies
NSJ Bioreagents
7 antibodies
Invitrogen Antibodies
12 antibodies
Atlas Antibodies
1 antibody
Boster Biological Technology
4 antibodies
Biorbyt
31 antibodies
Affinity Biosciences
1 antibody
HUABIO Research
1 antibody
NovoPro Bioscience Inc.
1 antibody
St John's Laboratory
3 antibodies
Abnova Corporation
5 antibodies
Abgent
2 antibodies
OriGene
2 antibodies
Acris Antibodies GmbH
2 antibodies
Bioworld Technology, Inc
1 antibody
Cusabio Biotech Co., Ltd
4 antibodies
GeneTex
3 antibodies
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Aviva Systems Biology
8 antibodies
BioLegend
3 antibodies
RabMAbs
2 antibodies
Creative Diagnostics
19 antibodies
ABEOMICS Inc.
2 antibodies
Bioss
1 antibody
Miltenyi Biotec
12 antibodies
Abbexa
11 antibodies
Creative Biolabs
33 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
52 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
EMD Millipore
1 antibody
MyBioSource
1 antibody
eBioscience, An Affymetrix Company
2 antibodies
CPTAC
2 antibodies