Tissue expression
Cell line expression
Protein structure
TLK1
Tousled like kinase 1KIAA0137, PKU-BETA
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
1 references | Polyclonal |
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GeneTex | ![]() |
3 references | Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Monoclonal |
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