Tissue expression
Cell line expression
Protein structure
H3C15
H3 clustered histone 15H3/n, H3/o, HIST2H3A
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015]
Top validated antibodies |
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Proteintech Group | 17168-1-AP | 403 references | Polyclonal |
WB
EL
ICC
FC |
|
antibodies-online | ABIN1449698 | 2 references | Polyclonal |
WB
EL
ICC
IHC |
|
NovoPro Bioscience Inc. | 111409 | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP2-52483 | Monoclonal |
WB
EL
FC
|
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LSBio | LS-C682366 | Monoclonal |
WB
EL |
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