Tissue expression
Cell line expression
Protein structure
HLA-E
Major histocompatibility complex, class I, EHLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NB120-6405 | 29 references | Monoclonal |
EL
ICC
IP
IHC
FC
BN
IEM
|
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Invitrogen Antibodies | 12-9953-41 | 18 references | Monoclonal |
FC
OA |
|
Proteintech Group | 66530-1-Ig | Monoclonal |
WB
EL
ICC
IHC
FC
|
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GeneTex | GTX11820 | 1 references | Monoclonal |
IP
IHC
FC
|
|
Atlas Antibodies | HPA031454 | Polyclonal |
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider