Tissue expression
Cell line expression
Protein structure
ERCC6
ERCC excision repair 6, chromatin remodeling factorARMD5, CKN2, CSB, RAD26
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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GeneTex | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
1 references | Polyclonal |
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