Tissue expression
Cell line expression
Protein structure

HLA-DPA1

Major histocompatibility complex, class II, DP alpha 1
HLA-DP1A 
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
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380 antibodies from 31 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
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6 antibodies
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1 antibody
OriGene
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5 antibodies
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3 antibodies
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1 antibody
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3 antibodies
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1 antibody
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1 antibody
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1 antibody
Aviva Systems Biology
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Arigo
2 antibodies
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2 antibodies
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15 antibodies
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2 antibodies
Creative Diagnostics
2 antibodies
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25 antibodies
MyBioSource
4 antibodies
Abbexa
8 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
MilliporeSigma / Merck KGaA
1 antibody
Leading Biology
2 antibodies
ProSci
1 antibody
GenWay
6 antibodies