Tissue expression
Cell line expression
Protein structure
ARHGAP8
Rho GTPase activating protein 8BPGAP1, FLJ20185
This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
Top validated antibodies |
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Atlas Antibodies | HPA069694 | Polyclonal |
ICC
IHC |
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Invitrogen Antibodies | PA5-67065 | Polyclonal |
ICC
IHC |
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antibodies-online | ABIN5075106 | Polyclonal |
ICC
IHC |
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LSBio | LS-B12042 | Polyclonal |
WB
IHC |
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Novus Biologicals | NBP2-57680 | Polyclonal |
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider