Tissue expression
Cell line expression
Protein structure
LEFTY1
Left-right determination factor 1LEFTB, LEFTYB
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016]
Top validated antibodies |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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antibodies-online | ![]() |
3 references | Polyclonal |
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Abnova Corporation | ![]() |
3 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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