DCANP1

This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq, Jul 2008]

Description

Dendritic cell associated nuclear protein

Tissue specificity

Not detected

Subcell location

Nucleoplasm, Nuclear bodies

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

5 (135444214 - 135447348)

Ensembl ID

ENSG00000251380  (ver. 103.38)

Orthologs

-

UniProt

Q8TF63

neXtProt

NX_Q8TF63

Human splice variants

Protein structure