ZNF224

This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein represses transcription of the aldolase A gene, which encodes a key enzyme in glycolysis. The encoded zinc-finger protein may also function as a transcriptional co-activator with Wilms' tumor protein 1 to regulate apoptotic genes in leukemia. [provided by RefSeq, Jul 2016]

Description

Zinc finger protein 224

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Transcription factors

Chromosome

19 (44094339 - 44109886)

Ensembl ID

ENSG00000267680  (ver. 103.38)

Orthologs

-

UniProt

Q9NZL3

neXtProt

NX_Q9NZL3

Human splice variants

Protein structure