DOC2B

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq, Jul 2008]

Description

Double C2 domain beta

Tissue specificity

Tissue enhanced (brain, retina)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

17 (142789 - 181650)

Ensembl ID

ENSG00000272636  (ver. 103.38)

Orthologs

Mouse Doc2b: ENSMUSG00000020848

UniProt

Q14184

neXtProt

NX_Q14184

Human splice variants
Mouse splice variants

Protein structure