Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
AIRE
Autoimmune regulatorAPECED, APS1, PGA1
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
Top validated antibodies |
|||||
| Novus Biologicals |  NB100-1063 |
1 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
|
| Proteintech Group | 22517-1-AP |
2 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| Everest Biotech | EB05507 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
||
| Invitrogen Antibodies | 14-9534-80 |
5 references | Monoclonal |
IHC
OA
|
|
| antibodies-online | ABIN950316 |
2 references | Polyclonal |
WB
EL
ICC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider