orb107096
antibody from Biorbyt
Targeting: RBPJ
CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- orb107096 - Provider product page
- Provider
- Biorbyt
- Product name
- RBPJ antibody
- Antibody type
- Polyclonal
- Description
- Rabbot polyclonal to RBPJ. Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 400 μl
- Storage
- Maintain refrigerated at 2-8°C. for up to 6 months. For long term storage store at -20°C. in small aliquots to prevent freeze-thaw cycles.
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Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of Ramos cell line lysates (35ug/lane) using RBPJ antibody (N-term)
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- WB analysis of human pancreas lysates/proteins at 20 µg per lane using RBPJ antibody
Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Confocal immunofluoroscence analysis of A2058 cell using RBPJ antibody (N-term)
Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of formalin-fixed paraffin embedded human stomach tissue using RBPJ antibody (N-term)