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ABCB11
ATP binding cassette subfamily B member 11ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-78690 |
2 references | Polyclonal |
WB
IHC
FC
OA
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| NSJ Bioreagents | R31844 |
3 references | Polyclonal |
WB
IHC
FC
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| antibodies-online | ABIN2840586 |
3 references | Polyclonal |
WB
IHC
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| Abgent | AP6110A |
2 references | Polyclonal |
WB
IHC
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| Atlas Antibodies | HPA019035 |
2 references | Polyclonal |
IHC
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