Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
DNMT1
DNA methyltransferase 1CXXC9, DNMT, MCMT
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  MA5-16169 |
3 references | Monoclonal |
WB
ICC
IP
IHC
FC
ChIP
OA
|
|
| Novus Biologicals | NB100-56519 |
120 references | Monoclonal |
WB
ICC
IP
IHC
FC
ChIP
|
|
| GeneTex | GTX116011 |
14 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
|
| Proteintech Group | 24206-1-AP |
45 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
| antibodies-online | ABIN252481 |
106 references | Monoclonal |
WB
ICC
IP
IHC
FC
ChIP
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider