DYNLT3

This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20. [provided by RefSeq, Mar 2010]

Description

Dynein light chain Tctex-type 3

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (37836757 - 37847571)

Ensembl ID

ENSG00000165169  (ver. 103.38)

Orthologs

Mouse Dynlt3: ENSMUSG00000031176

UniProt

P51808

neXtProt

NX_P51808

Human splice variants
Mouse splice variants

Protein structure