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antibody from Novus Biologicals
Targeting: BIRC5
API4, EPR-1, survivin
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ELISA Immunocytochemistry Immunoprecipitation Immunohistochemistry Flow cytometry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [347]
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- Western blot [8]
- Immunohistochemistry [5]
- Flow cytometry [1]
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- Product number
- NB500-201 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB500-201, RRID:AB_10001517
- Product name
- Rabbit Polyclonal Survivin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Canine, Feline, Guinea Pig, Hamster
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC.
NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.
Phase-I trial of survivin inhibition with EZN-3042 in dogs with spontaneous lymphoma.
Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation.
Inhibitory Effects of Indomethacin in Human MNNG/HOS Osteosarcoma Cell Line In Vitro.
Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation.
Essential oil of Cyphostemma juttae (Vitaceae): Chemical composition and antitumor mechanism in triple negative breast cancer cells.
Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma.
Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity.
The effect of non-steroidal anti-inflammatory drugs on osteosarcoma cells.
Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1.
CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells.
αvβ3 Integrin Mediates Radioresistance of Prostate Cancer Cells through Regulation of Survivin.
Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma.
Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.
Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide.
Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex.
Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series.
YM155 enhances the cytotoxic activity of etoposide against canine osteosarcoma cells.
Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562.
Integrative Histologic and Bioinformatics Analysis of BIRC5/Survivin Expression in Oral Squamous Cell Carcinoma.
Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line.
Exosomal survivin facilitates vesicle internalization.
Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3.
The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells.
Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway.
Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy.
Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer.
Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells.
The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells.
A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion.
Synthesis and biological evaluation of novel 2-arylvinyl-substituted naphtho[2,3-d]imidazolium halide derivatives as potent antitumor agents.
The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells.
Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription.
Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization.
Racial differences in the expression of inhibitors of apoptosis (IAP) proteins in extracellular vesicles (EV) from prostate cancer patients.
Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells.
Survivin and XIAP - two potential biological targets in follicular thyroid carcinoma.
Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.
Survivin expression, HPV positivity and microvessel density in oropharyngeal carcinomas and relationship with survival time.
Nuclear survivin promoted by acetylation is associated with the aggressive phenotype of oral squamous cell carcinoma.
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
Survivin expression pattern in the intestine of normoxic and ischemic rats.
Expression of survivin, MUC2 and MUC5 in colorectal cancer and their association with clinicopathological characteristics.
Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR‑ABL‑positive CML cells.
Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas.
Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair.
Anti-tumour efficacy of etoposide alone and in combination with piroxicam against canine osteosarcoma in a xenograft model.
Polyaspartamide-Based Nanoparticles Loaded with Fluticasone Propionate and the In Vitro Evaluation towards Cigarette Smoke Effects.
Mitochondrial CCAR2/DBC1 is required for cell survival against rotenone-induced mitochondrial stress.
A novel 4-arm DNA/RNA Nanoconstruct triggering Rapid Apoptosis of Triple Negative Breast Cancer Cells within 24 hours.
Prognostic Value of Angiogenesis and Survivin Expression in Patients with Glioblastoma.
Survivin and gliomas: A literature review.
Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction.
The Ska complex promotes Aurora B activity to ensure chromosome biorientation.
MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma.
Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling.
Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.
Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer.
Survivin mRNA-circulating tumor cells are associated with prostate cancer metastasis.
Survivin Modulates Squamous Cell Carcinoma-Derived Stem-Like Cell Proliferation, Viability and Tumor Formation in Vivo.
Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma.
The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance.
Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.
Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells.
PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer.
Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma.
Innovative delivery of siRNA to solid tumors by super carbonate apatite.
Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells.
Modulating the expression of survivin and other basal epidermal proteins protects human skin from UVB damage and oxidative stress.
Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer.
t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib.
Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy.
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.
miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin.
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.
No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo.
Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway.
TD-60 links RalA GTPase function to the CPC in mitosis.
Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis.
microRNA-mediated survivin control of pluripotency.
Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.
Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP).
Canine cutaneous melanocytic tumours: significance of β-catenin and survivin immunohistochemical expression.
Putative tumor suppression function of SIRT6 in endometrial cancer.
Survivin suppressor (YM155) enhances chemotherapeutic efficacy against canine histiocytic sarcoma in murine transplantation models.
The expression and role of MEKK3 in renal clear cell carcinoma.
SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.
Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.
MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.
MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.
Detection of high levels of Survivin-immunoglobulin M immune complex in sera from hepatitis C virus infected patients with cirrhosis.
AAG8 promotes carcinogenesis by activating STAT3.
Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.
Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma.
Prognostic utility of apoptosis index, Ki-67 and survivin expression in dogs with nasal carcinoma treated with orthovoltage radiation therapy.
Prognostic utility of apoptosis index, Ki-67 and survivin expression in dogs with nasal carcinoma treated with orthovoltage radiation therapy.
Ponatinib induces apoptosis in imatinib-resistant human mast cells by dephosphorylating mutant D816V KIT and silencing β-catenin signaling.
The cellular inhibitor of apoptosis protein-2 is a possible target of novel treatment for endometriosis.
The role of survivin in thyroid tumors: differences of expression in well-differentiated, non-well-differentiated, and anaplastic thyroid cancers.
Early diagnostic value of survivin and its alternative splice variants in breast cancer.
Yin Yang 1 regulates the transcriptional repression of Survivin.
Prognostic value of survivin and EGFR protein expression in triple-negative breast cancer (TNBC) patients.
The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.
Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST).
Inhibition of survivin influences the biological activities of canine histiocytic sarcoma cell lines.
Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer.
IGF-IR promotes prostate cancer growth by stabilizing α5β1 integrin protein levels.
Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction.
Prognostic impact of human papillomavirus status, survivin, and epidermal growth factor receptor expression on survival in patients treated with radiochemotherapy for very advanced nonresectable oropharyngeal cancer.
Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.
The role of p21 Waf1/Cip1 in large airway epithelium in smokers with and without COPD.
Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells.
DNMT1: an emerging target in the treatment of invasive urinary bladder cancer.
Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma.
Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response.
PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin.
Enhanced inhibition of bladder cancer cell growth by simultaneous knockdown of antiapoptotic Bcl-xL and survivin in combination with chemotherapy.
β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1.
Intratumoral concentration of estrogens and clinicopathological changes in ductal carcinoma in situ following aromatase inhibitor letrozole treatment.
Inhibition of STAT signalling in bladder cancer by diindolylmethane: relevance to cell adhesion, migration and proliferation.
Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.
Functional characterization of novel mutations affecting survivin (BIRC5)-mediated therapy resistance in head and neck cancer patients.
Epithelial-to-mesenchymal transition: immunohistochemical investigation of related molecules in canine cutaneous epithelial tumours.
Depletion of K-Ras promotes proteasome degradation of survivin.
HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.
Suppression of actopaxin impairs hepatocellular carcinoma metastasis through modulation of cell migration and invasion.
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML).
E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro.
Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress.
Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation.
Nutrient availability alters the effect of autophagy on sulindac sulfide-induced colon cancer cell apoptosis.
Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma.
Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells.
Nuclear survivin expression as a potentially useful tool for the diagnosis of canine cutaneous sebaceous lesions.
Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease.
Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.
Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.
Accumulation of α-synuclein triggered by presynaptic dysfunction.
Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer.
PSA regulates androgen receptor expression in prostate cancer cells.
Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells.
Total Survivin and acetylated Survivin correlate with distinct molecular subtypes of breast cancer.
Targeting X-linked inhibitor of apoptosis protein inhibits pancreatic cancer cell growth through p-Akt depletion.
Immunohistochemical investigation of cell cycle and apoptosis regulators (survivin, β-catenin, p53, caspase 3) in canine appendicular osteosarcoma.
Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification.
Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction.
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.
Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients.
Oestrogen-induced genes in ductal carcinoma in situ: their comparison with invasive ductal carcinoma.
Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models.
The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells.
Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain.
Expression of HuR, COX-2, and survivin in lung cancers; cytoplasmic HuR stabilizes cyclooxygenase-2 in squamous cell carcinomas.
Pigmented spindle cell nevus: clues for differentiating it from spindle cell malignant melanoma. A comprehensive survey including clinicopathologic, immunohistochemical, and FISH studies.
Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients.
Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
Russia pledges $4 billion for Pharma-2020 plan.
STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma.
The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines.
Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
The prostaglandin E2 receptor, EP2, regulates survivin expression via an EGFR/STAT3 pathway in UVB-exposed mouse skin.
Garlic constituent diallyl trisulfide suppresses x-linked inhibitor of apoptosis protein in prostate cancer cells in culture and in vivo.
Sulindac sulfide induces autophagic death in gastric epithelial cells via survivin down-regulation: a mechanism of NSAIDs-induced gastric injury.
The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro.
Survivin is released from cancer cells via exosomes.
p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation.
Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles.
Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.
Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.
The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro.
Concomitant expression of HER2 and HIF-1alpha is a predictor of poor prognosis in uterine cervical carcinoma treated with concurrent chemoradiotherapy: prospective analysis (KGROG0501).
Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules.
Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear.
BRCA1-IRIS overexpression promotes cisplatin resistance in ovarian cancer cells.
Immunohistochemical detection of survivin in canine lymphoma.
Integrative genome comparison of primary and metastatic melanomas.
Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.
Detection of autoantibodies against survivin in sera from cancer dogs.
Detection of autoantibodies against survivin in sera from cancer dogs.
Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia.
Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis.
An otoprotective role for the apoptosis inhibitor protein survivin.
A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC.
Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells.
Differential regulation of TP73 isoforms by 1α,25-dihydroxyvitamin D3 and survivin in human colon and breast carcinomas.
Tumor survivin is downregulated by the antisense oligonucleotide LY2181308: a proof-of-concept, first-in-human dose study.
Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin.
Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice.
Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B.
Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice.
Relationship between the expression of cyclooxygenase-2 and survivin in primary pterygium.
Survival responses of human embryonic stem cells to DNA damage.
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells.
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.
TNFR2-deficient memory CD8 T cells provide superior protection against tumor cell growth.
Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study.
Expression of the antiapoptosis gene Survivin predicts poor prognosis of stage III gastric adenocarcinoma.
Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin.
Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells.
ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence.
Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.
Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.
Seliciclib (CYC202, R-roscovitine) enhances the antitumor effect of doxorubicin in vivo in a breast cancer xenograft model.
Impaired insulin-mediated vasorelaxation in diabetic Goto-Kakizaki rats is caused by impaired Akt phosphorylation.
Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance.
Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity.
Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferation.
Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential.
Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.
Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis.
Fas-mediated killing of primary prostate cancer cells is increased by mitoxantrone and docetaxel.
A survivin-ran complex regulates spindle formation in tumor cells.
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.
BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis.
AML1/ETO-induced survivin expression inhibits transcriptional regulation of myeloid differentiation.
Antisense-mediated inhibition of survivin, hTERT and VEGF in bladder cancer cells in vitro and in vivo.
Neoadjuvant docetaxel and capecitabine in patients with high risk prostate cancer.
Tumor cell dependence on Ran-GTP-directed mitosis.
Expression of the inhibitor of apoptosis protein family in multiple sclerosis reveals a potential immunomodulatory role during autoimmune mediated demyelination.
Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis.
NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas.
pp32/PHAPI determines the apoptosis response of non-small-cell lung cancer.
Survivin expression in glioblastomas correlates with proliferation, but not with apoptosis.
Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibition.
Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure.
Nuclear survivin has reduced stability and is not cytoprotective.
Hsp60 regulation of tumor cell apoptosis.
Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia.
Imatinib targeting of KIT-mutant oncoprotein in melanoma.
Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis.
Adeno-sh-beta-catenin abolishes ischemic preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2, and survivin in ischemic rat myocardium.
T-cell responses to survivin in cancer patients undergoing radiation therapy.
Attenuation of apoptosis by chromogranin A-induced Akt and survivin pathways in prostate cancer cells.
Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40.
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed.
Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments.
Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder.
Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition?
Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition?
Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.
Autoantibodies to the inhibitor of apoptosis protein survivin in patients with brain tumors.
Nuclear export is essential for the tumor-promoting activity of survivin.
Formin-2 is required for spindle migration and for the late steps of cytokinesis in mouse oocytes.
Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis.
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies.
Dynamic intracellular survivin in oral squamous cell carcinoma: underlying molecular mechanism and potential as an early prognostic marker.
Beta-catenin overexpression reduces myocardial infarct size through differential effects on cardiomyocytes and cardiac fibroblasts.
Prognostic significance of the Epstein-Barr virus, p53, Bcl-2, and survivin in nasopharyngeal cancer.
Nucleocytoplasmic shuttling and the biological activity of mouse survivin are regulated by an active nuclear export signal.
Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients.
Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
Survivin, a cancer target with an emerging role in normal adult tissues.
Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis.
Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis.
Expression of cytoplasmic and nuclear Survivin in primary and secondary human glioblastoma.
TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo.
TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo.
Celecoxib decreases Ki-67 proliferative index in active smokers.
Angiotensin II and tumor necrosis factor-alpha upregulate survivin and Kruppel-like factor 5 in smooth muscle cells: Potential relevance to vein graft hyperplasia.
Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.
Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation.
Adenoviral infection of survivin antisense sensitizes prostate cancer cells to etoposide in vivo.
Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells.
Use of fuzzy neural networks in modeling relationships of HPV infection with apoptotic and proliferation markers in potentially malignant oral lesions.
Survivin inhibits anti-growth effect of p53 activated by aurora B.
Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion.
4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin.
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1.
Survivin expression predicts poorer prognosis in patients with areca quid chewing-related oral squamous cell carcinoma in Taiwan.
A dopamine D4 receptor antagonist attenuates ischemia-induced neuronal cell damage via upregulation of neuronal apoptosis inhibitory protein.
Expression of cell cycle markers and human papillomavirus infection in oral squamous cell carcinoma: use of fuzzy neural networks.
A small C-terminal sequence of Aurora B is responsible for localization and function.
Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome.
Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.
Survivin is a negative prognostic marker in medulloblastoma.
Cellular localisation of survivin: impact on the prognosis in colorectal cancer.
A mutation found in the promoter region of the human survivin gene is correlated to overexpression of survivin in cancer cells.
Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms.
Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer.
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer.
Cancer-specific activation of the survivin promoter and its potential use in gene therapy.
Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes.
Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma.
Survivin enhances Fas ligand expression via up-regulation of specificity protein 1-mediated gene transcription in colon cancer cells.
Survivin enhances Fas ligand expression via up-regulation of specificity protein 1-mediated gene transcription in colon cancer cells.
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression.
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle.
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.
COX-2-dependent stabilization of survivin in non-small cell lung cancer.
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells.
Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis.
Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray.
Survivin expression in ovarian carcinoma: correlation with apoptotic markers and prognosis.
Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival.
IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression.
IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression.
HPV DNA and survivin expression in epithelial oral carcinogenesis: a relationship?
Megakaryocytes express functional Aurora-B kinase in endomitosis.
Roles of iNOS and nNOS in sepsis-induced pulmonary apoptosis.
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis.
A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis.
A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis.
Nuclear expression of Survivin in paediatric ependymomas and choroid plexus tumours correlates with morphologic tumour grade.
Regulation of survivin function by Hsp90.
Gene expression and mitotic exit induced by microtubule-stabilizing drugs.
Characterization of antigen processing machinery and Survivin expression in tonsillar squamous cell carcinoma.
Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.
Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis.
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces antiapoptotic and proapoptotic signals in acute myeloid leukemia.
Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma.
Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells.
Survivin expression in oral squamous cell carcinoma.
Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway.
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.
Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
Prognostic importance of survivin in breast cancer.
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
Inhibitor of apoptosis protein survivin regulates vascular injury.
Induction of apoptosis by bexarotene in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action.
Regulation of microtubule stability and mitotic progression by survivin.
2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells.
A p34(cdc2) survival checkpoint in cancer.
A p34(cdc2) survival checkpoint in cancer.
Increased expression of survivin in gastric cancer patients and in first degree relatives.
Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas.
Quantitatively determined survivin expression levels are of prognostic value in human gliomas.
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.
Differential subcellular localization of functionally divergent survivin splice variants.
Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning.
Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning.
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis.
Brown M, Zhang W, Yan D, Kenath R, Le L, Wang H, Delitto D, Ostrov D, Robertson K, Liu C, Pham K
PloS one 2020;15(1):e0226917
PloS one 2020;15(1):e0226917
NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.
Nourreddine S, Lavoie G, Paradis J, Ben El Kadhi K, Méant A, Aubert L, Grondin B, Gendron P, Chabot B, Bouvier M, Carreno S, Roux PP
Cell reports 2020 May 19;31(7):107660
Cell reports 2020 May 19;31(7):107660
Phase-I trial of survivin inhibition with EZN-3042 in dogs with spontaneous lymphoma.
Thamm DH, Joseph JK, Rose BJ, Meuten TK, Weishaar KM
BMC veterinary research 2020 Mar 24;16(1):97
BMC veterinary research 2020 Mar 24;16(1):97
Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation.
Erdogan S, Turkekul K
Journal of food biochemistry 2020 Jul;44(7):e13253
Journal of food biochemistry 2020 Jul;44(7):e13253
Inhibitory Effects of Indomethacin in Human MNNG/HOS Osteosarcoma Cell Line In Vitro.
Mirshahidi S, de Necochea-Campion R, Moretta A, Williams NL, Reeves ME, Otoukesh S, Mirshahidi HR, Khosrowpour S, Duerksen-Hughes P, Zuckerman LM
Cancer investigation 2020 Jan;38(1):23-36
Cancer investigation 2020 Jan;38(1):23-36
Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation.
Liang C, Zhang Z, Chen Q, Yan H, Zhang M, Zhou L, Xu J, Lu W, Wang F
The Journal of cell biology 2020 Feb 3;219(2)
The Journal of cell biology 2020 Feb 3;219(2)
Essential oil of Cyphostemma juttae (Vitaceae): Chemical composition and antitumor mechanism in triple negative breast cancer cells.
Zito P, Labbozzetta M, Notarbartolo M, Sajeva M, Poma P
PloS one 2019;14(3):e0214594
PloS one 2019;14(3):e0214594
Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma.
Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, Zhang J, Pan J
Molecular cancer 2019 Nov 13;18(1):159
Molecular cancer 2019 Nov 13;18(1):159
Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity.
Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, Hartman J, Fischbach C, Lin H, Cerione RA, Antonyak MA
Developmental cell 2019 May 6;49(3):393-408.e7
Developmental cell 2019 May 6;49(3):393-408.e7
The effect of non-steroidal anti-inflammatory drugs on osteosarcoma cells.
Zuckerman LM, Frames WL, Elsissy JG, Shields TG, de Necochea-Campion R, Mirshahidi HR, Williams NL, Mirshahidi S
European review for medical and pharmacological sciences 2019 Mar;23(6):2681-2690
European review for medical and pharmacological sciences 2019 Mar;23(6):2681-2690
Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1.
Ketteler J, Panic A, Reis H, Wittka A, Maier P, Herskind C, Yagüe E, Jendrossek V, Klein D
Journal of clinical medicine 2019 Mar 12;8(3)
Journal of clinical medicine 2019 Mar 12;8(3)
CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells.
Kim W, Ryu J, Kim JE
International journal of molecular sciences 2019 Jan 1;20(1)
International journal of molecular sciences 2019 Jan 1;20(1)
αvβ3 Integrin Mediates Radioresistance of Prostate Cancer Cells through Regulation of Survivin.
Wang T, Huang J, Vue M, Alavian MR, Goel HL, Altieri DC, Languino LR, FitzGerald TJ
Molecular cancer research : MCR 2019 Feb;17(2):398-408
Molecular cancer research : MCR 2019 Feb;17(2):398-408
Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma.
Liu T, Liu J, Chen Q, Jin S, Mi S, Shao W, Kudo Y, Zeng S, Qi G
Oncology letters 2019 Feb;17(2):2040-2046
Oncology letters 2019 Feb;17(2):2040-2046
Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.
Hwang JY, Park JH, Kim MJ, Kim WJ, Ha KT, Choi BT, Lee SY, Shin HK
Cancer letters 2019 Feb 28;443:25-33
Cancer letters 2019 Feb 28;443:25-33
Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide.
Lionetti MC, Mutti F, Soldati E, Fumagalli MR, Coccé V, Colombo G, Astori E, Miani A, Milzani A, Dalle-Donne I, Ciusani E, Costantini G, La Porta CAM
International journal of environmental research and public health 2019 Feb 23;16(4)
International journal of environmental research and public health 2019 Feb 23;16(4)
Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex.
Abad MA, Ruppert JG, Buzuk L, Wear M, Zou J, Webb KM, Kelly DA, Voigt P, Rappsilber J, Earnshaw WC, Jeyaprakash AA
The Journal of cell biology 2019 Dec 2;218(12):3912-3925
The Journal of cell biology 2019 Dec 2;218(12):3912-3925
Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series.
Kubo T, Tsurita G, Hirohashi Y, Yasui H, Ota Y, Watanabe K, Murai A, Matsuo K, Asanuma H, Shima H, Wada S, Nakatsugawa M, Kanaseki T, Tsukahara T, Mizuguchi T, Hirata K, Takemasa I, Imai K, Sato N, Torigoe T
Cancer science 2019 Aug;110(8):2386-2395
Cancer science 2019 Aug;110(8):2386-2395
YM155 enhances the cytotoxic activity of etoposide against canine osteosarcoma cells.
Ong SM, Saeki K, Kok MK, Nakagawa T, Nishimura R
The Journal of veterinary medical science 2019 Aug 24;81(8):1182-1190
The Journal of veterinary medical science 2019 Aug 24;81(8):1182-1190
Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
Ferraro M, Di Vincenzo S, Dino P, Bucchieri S, Cipollina C, Gjomarkaj M, Pace E
Experimental gerontology 2019 Apr;118:78-87
Experimental gerontology 2019 Apr;118:78-87
Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562.
Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O
Gene 2019 Apr 15;692:217-222
Gene 2019 Apr 15;692:217-222
Integrative Histologic and Bioinformatics Analysis of BIRC5/Survivin Expression in Oral Squamous Cell Carcinoma.
Troiano G, Guida A, Aquino G, Botti G, Losito NS, Papagerakis S, Pedicillo MC, Ionna F, Longo F, Cantile M, Pennella A, Lo Russo L, Di Gioia G, Mariggiò MA, Lo Muzio L, Pannone G
International journal of molecular sciences 2018 Sep 8;19(9)
International journal of molecular sciences 2018 Sep 8;19(9)
Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line.
Gock M, Mullins CS, Harnack C, Prall F, Ramer R, Göder A, Krämer OH, Klar E, Linnebacher M
World journal of gastroenterology 2018 Sep 7;24(33):3749-3759
World journal of gastroenterology 2018 Sep 7;24(33):3749-3759
Exosomal survivin facilitates vesicle internalization.
Gonda A, Kabagwira J, Senthil GN, Ferguson Bennit HR, Neidigh JW, Khan S, Wall NR
Oncotarget 2018 Oct 9;9(79):34919-34934
Oncotarget 2018 Oct 9;9(79):34919-34934
Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3.
Humphry NJ, Wheatley SP
Biology open 2018 Oct 22;7(10)
Biology open 2018 Oct 22;7(10)
The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells.
Giuliani A, Cirilli I, Prattichizzo F, Mensà E, Fulgenzi G, Sabbatinelli J, Graciotti L, Olivieri F, Procopio AD, Tiano L, Rippo MR
Aging 2018 Oct 21;10(10):2855-2873
Aging 2018 Oct 21;10(10):2855-2873
Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway.
Erdogan S, Turkekul K, Dibirdik I, Doganlar O, Doganlar ZB, Bilir A, Oktem G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:793-805
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:793-805
Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy.
Lee HS, Carmena M, Liskovykh M, Peat E, Kim JH, Oshimura M, Masumoto H, Teulade-Fichou MP, Pommier Y, Earnshaw WC, Larionov V, Kouprina N
Cancer research 2018 Nov 1;78(21):6282-6296
Cancer research 2018 Nov 1;78(21):6282-6296
Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer.
Dizdar L, Jünemann LM, Werner TA, Verde PE, Baldus SE, Stoecklein NH, Knoefel WT, Krieg A
Oncology letters 2018 Mar;15(3):3779-3789
Oncology letters 2018 Mar;15(3):3779-3789
Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells.
Rauch A, Carlstedt A, Emmerich C, Mustafa AM, Göder A, Knauer SK, Linnebacher M, Heinzel T, Krämer OH
Oncotarget 2018 Jun 12;9(45):27835-27850
Oncotarget 2018 Jun 12;9(45):27835-27850
The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells.
Kiweler N, Brill B, Wirth M, Breuksch I, Laguna T, Dietrich C, Strand S, Schneider G, Groner B, Butter F, Heinzel T, Brenner W, Krämer OH
Archives of toxicology 2018 Jul;92(7):2227-2243
Archives of toxicology 2018 Jul;92(7):2227-2243
A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion.
Liang C, Chen Q, Yi Q, Zhang M, Yan H, Zhang B, Zhou L, Zhang Z, Qi F, Ye S, Wang F
EMBO reports 2018 Jan;19(1):43-56
EMBO reports 2018 Jan;19(1):43-56
Synthesis and biological evaluation of novel 2-arylvinyl-substituted naphtho[2,3-d]imidazolium halide derivatives as potent antitumor agents.
Wei Q, Li J, Tang F, Yin Y, Zhao Y, Yao Q
European journal of medicinal chemistry 2018 Jan 20;144:504-516
European journal of medicinal chemistry 2018 Jan 20;144:504-516
The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells.
Taglieri L, Rubinacci G, Giuffrida A, Carradori S, Scarpa S
Investigational new drugs 2018 Feb;36(1):28-35
Investigational new drugs 2018 Feb;36(1):28-35
Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription.
Novais-Cruz M, Alba Abad M, van IJcken WF, Galjart N, Jeyaprakash AA, Maiato H, Ferrás C
eLife 2018 Aug 6;7
eLife 2018 Aug 6;7
Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization.
Unruhe-Knauf B, Knauer SK
Methods in molecular biology (Clifton, N.J.) 2017;1510:47-59
Methods in molecular biology (Clifton, N.J.) 2017;1510:47-59
Racial differences in the expression of inhibitors of apoptosis (IAP) proteins in extracellular vesicles (EV) from prostate cancer patients.
Khan S, Simpson J, Lynch JC, Turay D, Mirshahidi S, Gonda A, Sanchez TW, Casiano CA, Wall NR
PloS one 2017;12(10):e0183122
PloS one 2017;12(10):e0183122
Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells.
Taglieri L, De Iuliis F, Giuffrida A, Giantulli S, Silvestri I, Scarpa S
Oncology letters 2017 Sep;14(3):3832-3838
Oncology letters 2017 Sep;14(3):3832-3838
Survivin and XIAP - two potential biological targets in follicular thyroid carcinoma.
Werner TA, Dizdar L, Nolten I, Riemer JC, Mersch S, Schütte SC, Driemel C, Verde PE, Raba K, Topp SA, Schott M, Knoefel WT, Krieg A
Scientific reports 2017 Sep 12;7(1):11383
Scientific reports 2017 Sep 12;7(1):11383
Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.
Bradford EM, Ryu SH, Singh AP, Lee G, Goretsky T, Sinh P, Williams DB, Cloud AL, Gounaris E, Patel V, Lamping OF, Lynch EB, Moyer MP, De Plaen IG, Shealy DJ, Yang GY, Barrett TA
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1886-1897
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1886-1897
Survivin expression, HPV positivity and microvessel density in oropharyngeal carcinomas and relationship with survival time.
Tastekin E, Caloglu VY, Durankus NK, Sut N, Turkkan G, Can N, Puyan FO, Caloglu M
Archives of medical science : AMS 2017 Oct;13(6):1467-1473
Archives of medical science : AMS 2017 Oct;13(6):1467-1473
Nuclear survivin promoted by acetylation is associated with the aggressive phenotype of oral squamous cell carcinoma.
Liu S, Shi L, Yang X, Ye D, Wang T, Dong C, Guo W, Liao Y, Song H, Xu D, Hu J, Zhang Z, Deng J
Cell cycle (Georgetown, Tex.) 2017 May 3;16(9):894-902
Cell cycle (Georgetown, Tex.) 2017 May 3;16(9):894-902
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
Chen B, Wei W, Ma L, Yang B, Gill RM, Chua MS, Butte AJ, So S
Gastroenterology 2017 Jun;152(8):2022-2036
Gastroenterology 2017 Jun;152(8):2022-2036
Survivin expression pattern in the intestine of normoxic and ischemic rats.
Scheer A, Knauer SK, Verhaegh R
BMC gastroenterology 2017 Jun 14;17(1):76
BMC gastroenterology 2017 Jun 14;17(1):76
Expression of survivin, MUC2 and MUC5 in colorectal cancer and their association with clinicopathological characteristics.
Wang H, Jin S, Lu H, Mi S, Shao W, Zuo X, Yin H, Zeng S, Shimamoto F, Qi G
Oncology letters 2017 Jul;14(1):1011-1016
Oncology letters 2017 Jul;14(1):1011-1016
Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AK, Altieri DC, Messick TE, Lieberman PM
Oncotarget 2017 Jan 31;8(5):7248-7264
Oncotarget 2017 Jan 31;8(5):7248-7264
Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR‑ABL‑positive CML cells.
Zhang J, Jin Y, Pan J
Molecular medicine reports 2017 Dec;16(6):9217-9223
Molecular medicine reports 2017 Dec;16(6):9217-9223
Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas.
Dizdar L, Tomczak M, Werner TA, Safi SA, Riemer JC, Verde PE, Stoecklein NH, Knoefel WT, Krieg A
Oncology letters 2017 Dec;14(6):6847-6856
Oncology letters 2017 Dec;14(6):6847-6856
Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair.
Magadum A, Ding Y, He L, Kim T, Vasudevarao MD, Long Q, Yang K, Wickramasinghe N, Renikunta HV, Dubois N, Weidinger G, Yang Q, Engel FB
Cell research 2017 Aug;27(8):1002-1019
Cell research 2017 Aug;27(8):1002-1019
Anti-tumour efficacy of etoposide alone and in combination with piroxicam against canine osteosarcoma in a xenograft model.
Ong SM, Saeki K, Kok MK, Tanaka Y, Choisunirachon N, Yoshitake R, Nishimura R, Nakagawa T
Research in veterinary science 2017 Aug;113:130-135
Research in veterinary science 2017 Aug;113:130-135
Polyaspartamide-Based Nanoparticles Loaded with Fluticasone Propionate and the In Vitro Evaluation towards Cigarette Smoke Effects.
Craparo EF, Ferraro M, Pace E, Bondì ML, Giammona G, Cavallaro G
Nanomaterials (Basel, Switzerland) 2017 Aug 13;7(8)
Nanomaterials (Basel, Switzerland) 2017 Aug 13;7(8)
Mitochondrial CCAR2/DBC1 is required for cell survival against rotenone-induced mitochondrial stress.
Kim W, Cheon MG, Kim JE
Biochemical and biophysical research communications 2017 Apr 15;485(4):782-789
Biochemical and biophysical research communications 2017 Apr 15;485(4):782-789
A novel 4-arm DNA/RNA Nanoconstruct triggering Rapid Apoptosis of Triple Negative Breast Cancer Cells within 24 hours.
Tung J, Tew LS, Hsu YM, Khung YL
Scientific reports 2017 Apr 11;7(1):793
Scientific reports 2017 Apr 11;7(1):793
Prognostic Value of Angiogenesis and Survivin Expression in Patients with Glioblastoma.
Tastekin E, Caloglu VY, Puyan FO, Tokuc B, Caloglu M, Yalta TD, Can N, Guler B
Turkish neurosurgery 2016;26(4):484-90
Turkish neurosurgery 2016;26(4):484-90
Survivin and gliomas: A literature review.
Varughese RK, Torp SH
Oncology letters 2016 Sep;12(3):1679-1686
Oncology letters 2016 Sep;12(3):1679-1686
Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction.
Genshaft AS, Li S, Gallant CJ, Darmanis S, Prakadan SM, Ziegler CG, Lundberg M, Fredriksson S, Hong J, Regev A, Livak KJ, Landegren U, Shalek AK
Genome biology 2016 Sep 19;17(1):188
Genome biology 2016 Sep 19;17(1):188
The Ska complex promotes Aurora B activity to ensure chromosome biorientation.
Redli PM, Gasic I, Meraldi P, Nigg EA, Santamaria A
The Journal of cell biology 2016 Oct 10;215(1):77-93
The Journal of cell biology 2016 Oct 10;215(1):77-93
MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
Makii C, Oda K, Ikeda Y, Sone K, Hasegawa K, Uehara Y, Nishijima A, Asada K, Koso T, Fukuda T, Inaba K, Oki S, Machino H, Kojima M, Kashiyama T, Mori-Uchino M, Arimoto T, Wada-Hiraike O, Kawana K, Yano T, Fujiwara K, Aburatani H, Osuga Y, Fujii T
Oncotarget 2016 Nov 15;7(46):75328-75338
Oncotarget 2016 Nov 15;7(46):75328-75338
TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma.
Lettini G, Sisinni L, Condelli V, Matassa DS, Simeon V, Maddalena F, Gemei M, Lopes E, Vita G, Del Vecchio L, Esposito F, Landriscina M
Cell death and differentiation 2016 Nov 1;23(11):1792-1803
Cell death and differentiation 2016 Nov 1;23(11):1792-1803
Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling.
Wu X, Tang W, Marquez RT, Li K, Highfill CA, He F, Lian J, Lin J, Fuchs JR, Ji M, Li L, Xu L
Oncotarget 2016 Mar 8;7(10):11708-23
Oncotarget 2016 Mar 8;7(10):11708-23
Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, Oki E, Kitao H, Maehara Y
Nature communications 2016 Mar 31;7:11117
Nature communications 2016 Mar 31;7:11117
Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer.
Alzoubi S, Brody L, Rahman S, Mahul-Mellier AL, Mercado N, Ito K, El-Bahrawy M, Silver A, Boobis A, Bell JD, Hajji N
Oncotarget 2016 Jul 12;7(28):44505-44521
Oncotarget 2016 Jul 12;7(28):44505-44521
Survivin mRNA-circulating tumor cells are associated with prostate cancer metastasis.
Wang H, Yang M, Xu J, Zou B, Zhou Q, Bian J, Wang X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):723-7
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):723-7
Survivin Modulates Squamous Cell Carcinoma-Derived Stem-Like Cell Proliferation, Viability and Tumor Formation in Vivo.
Lotti R, Palazzo E, Petrachi T, Dallaglio K, Saltari A, Truzzi F, Quadri M, Puviani M, Maiorana A, Marconi A, Pincelli C
International journal of molecular sciences 2016 Jan 12;17(1)
International journal of molecular sciences 2016 Jan 12;17(1)
Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma.
Werner TA, Tamkan-Ölcek Y, Dizdar L, Riemer JC, Wolf A, Cupisti K, Verde PE, Knoefel WT, Krieg A
British journal of cancer 2016 Feb 16;114(4):427-34
British journal of cancer 2016 Feb 16;114(4):427-34
The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance.
Kreger BT, Johansen ER, Cerione RA, Antonyak MA
Cancers 2016 Dec 9;8(12)
Cancers 2016 Dec 9;8(12)
Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.
Nonagase Y, Yonesaka K, Kawakami H, Watanabe S, Haratani K, Takahama T, Takegawa N, Ueda H, Tanizaki J, Hayashi H, Yoshida T, Takeda M, Chiba Y, Tamura T, Nakagawa K, Tsurutani J
Oncotarget 2016 Dec 20;7(51):84860-84871
Oncotarget 2016 Dec 20;7(51):84860-84871
Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells.
Pace E, Di Vincenzo S, Ferraro M, Bruno A, Dino P, Bonsignore MR, Battaglia S, Saibene F, Lanata L, Gjomarkaj M
Experimental gerontology 2016 Aug;81:119-28
Experimental gerontology 2016 Aug;81:119-28
PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer.
Qi G, Kudo Y, Tang B, Liu T, Jin S, Liu J, Zuo X, Mi S, Shao W, Ma X, Tsunematsu T, Ishimaru N, Zeng S, Tatsuka M, Shimamoto F
Oncotarget 2016 Apr 5;7(14):18812-24
Oncotarget 2016 Apr 5;7(14):18812-24
Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma.
Locke FL, Menges M, Veerapathran A, Coppola D, Gabrilovich D, Anasetti C
Journal for immunotherapy of cancer 2015;3:20
Journal for immunotherapy of cancer 2015;3:20
Innovative delivery of siRNA to solid tumors by super carbonate apatite.
Wu X, Yamamoto H, Nakanishi H, Yamamoto Y, Inoue A, Tei M, Hirose H, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Hossain S, Akaike T, Matsuura N, Doki Y, Mori M
PloS one 2015;10(3):e0116022
PloS one 2015;10(3):e0116022
Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells.
Yamazaki H, Takagi S, Hosoya K, Okumura M
Veterinary journal (London, England : 1997) 2015 Sep;205(3):375-80
Veterinary journal (London, England : 1997) 2015 Sep;205(3):375-80
Modulating the expression of survivin and other basal epidermal proteins protects human skin from UVB damage and oxidative stress.
Labarrade F, Bergeron L, Serre C, Lebleu A, Busuttil V, Botto JM, Domloge N
Journal of cosmetic dermatology 2015 Sep;14(3):191-203
Journal of cosmetic dermatology 2015 Sep;14(3):191-203
Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer.
Mehta A, Zhang L, Boufraqech M, Liu-Chittenden Y, Zhang Y, Patel D, Davis S, Rosenberg A, Ylaya K, Aufforth R, Li Z, Shen M, Kebebew E
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Sep 15;21(18):4123-32
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Sep 15;21(18):4123-32
t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib.
Christenson JL, Denny EC, Kane SE
Oncotarget 2015 Oct 20;6(32):33134-45
Oncotarget 2015 Oct 20;6(32):33134-45
Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy.
Artesi M, Kroonen J, Bredel M, Nguyen-Khac M, Deprez M, Schoysman L, Poulet C, Chakravarti A, Kim H, Scholtens D, Seute T, Rogister B, Bours V, Robe PA
Neuro-oncology 2015 Mar;17(3):392-406
Neuro-oncology 2015 Mar;17(3):392-406
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.
Bonora M, Wieckowsk MR, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, Pinton P
Oncogene 2015 Mar 19;34(12):1608
Oncogene 2015 Mar 19;34(12):1608
miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin.
Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, Molenaar JJ, Bohrer A, Knauer S, Speleman F, Epple M, Kozlova D, Yoon S, Baek K, Vandesompele J, Eggert A, Schramm A, Schulte JH
International journal of cancer 2015 Mar 15;136(6):1308-20
International journal of cancer 2015 Mar 15;136(6):1308-20
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.
Meidhof S, Brabletz S, Lehmann W, Preca BT, Mock K, Ruh M, Schüler J, Berthold M, Weber A, Burk U, Lübbert M, Puhr M, Culig Z, Wellner U, Keck T, Bronsert P, Küsters S, Hopt UT, Stemmler MP, Brabletz T
EMBO molecular medicine 2015 Jun;7(6):831-47
EMBO molecular medicine 2015 Jun;7(6):831-47
No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo.
Vogt N, Abramov D, Koch K, Masqué-Soler N, Szczepanowski M, Klapper W
Leukemia & lymphoma 2015 Jul;56(7):2134-40
Leukemia & lymphoma 2015 Jul;56(7):2134-40
Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway.
Yi XP, Han T, Li YX, Long XY, Li WZ
Molecular medicine reports 2015 Jul;12(1):601-8
Molecular medicine reports 2015 Jul;12(1):601-8
TD-60 links RalA GTPase function to the CPC in mitosis.
Papini D, Langemeyer L, Abad MA, Kerr A, Samejima I, Eyers PA, Jeyaprakash AA, Higgins JM, Barr FA, Earnshaw WC
Nature communications 2015 Jul 9;6:7678
Nature communications 2015 Jul 9;6:7678
Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis.
Sadowski SM, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, Li Z, Shen M, Kebebew E
Oncotarget 2015 Jul 20;6(20):18038-49
Oncotarget 2015 Jul 20;6(20):18038-49
microRNA-mediated survivin control of pluripotency.
Kapinas K, Kim H, Mandeville M, Martin-Buley LA, Croce CM, Lian JB, van Wijnen AJ, Stein JL, Altieri DC, Stein GS
Journal of cellular physiology 2015 Jan;230(1):63-70
Journal of cellular physiology 2015 Jan;230(1):63-70
Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.
Ramírez-Labrada A, López-Royuela N, Jarauta V, Galán-Malo P, Azaceta G, Palomera L, Pardo J, Anel A, Marzo I, Naval J
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2015 Feb;17(2):121-32
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2015 Feb;17(2):121-32
Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
Lan L, Appelman C, Smith AR, Yu J, Larsen S, Marquez RT, Liu H, Wu X, Gao P, Roy A, Anbanandam A, Gowthaman R, Karanicolas J, De Guzman RN, Rogers S, Aubé J, Ji M, Cohen RS, Neufeld KL, Xu L
Molecular oncology 2015 Aug;9(7):1406-20
Molecular oncology 2015 Aug;9(7):1406-20
Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP).
Valenzuela MM, Ferguson Bennit HR, Gonda A, Diaz Osterman CJ, Hibma A, Khan S, Wall NR
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2015 Aug;8(2):65-73
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2015 Aug;8(2):65-73
Canine cutaneous melanocytic tumours: significance of β-catenin and survivin immunohistochemical expression.
Bongiovanni L, D'Andrea A, Porcellato I, Ciccarelli A, Malatesta D, Romanucci M, Della Salda L, Mechelli L, Brachelente C
Veterinary dermatology 2015 Aug;26(4):270-e59
Veterinary dermatology 2015 Aug;26(4):270-e59
Putative tumor suppression function of SIRT6 in endometrial cancer.
Fukuda T, Wada-Hiraike O, Oda K, Tanikawa M, Makii C, Inaba K, Miyasaka A, Miyamoto Y, Yano T, Maeda D, Sasaki T, Kawana K, Fukayama M, Osuga Y, Fujii T
FEBS letters 2015 Aug 4;589(17):2274-81
FEBS letters 2015 Aug 4;589(17):2274-81
Survivin suppressor (YM155) enhances chemotherapeutic efficacy against canine histiocytic sarcoma in murine transplantation models.
Yamazaki H, Takagi S, Hosoya K, Okumura M
Research in veterinary science 2015 Apr;99:137-44
Research in veterinary science 2015 Apr;99:137-44
The expression and role of MEKK3 in renal clear cell carcinoma.
Lu H, Cao X, Chen Q, Chen L, Chen L, Gan M
Anatomical record (Hoboken, N.J. : 2007) 2015 Apr;298(4):727-34
Anatomical record (Hoboken, N.J. : 2007) 2015 Apr;298(4):727-34
SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.
Sulaiman MK, Chu Z, Blanco VM, Vallabhapurapu SD, Franco RS, Qi X
Molecular cancer 2015 Apr 8;14:78
Molecular cancer 2015 Apr 8;14:78
Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.
Zhang L, Zhang Y, Mehta A, Boufraqech M, Davis S, Wang J, Tian Z, Yu Z, Boxer MB, Kiefer JA, Copland JA, Smallridge RC, Li Z, Shen M, Kebebew E
Oncotarget 2015 Apr 20;6(11):9073-85
Oncotarget 2015 Apr 20;6(11):9073-85
MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.
Cao XQ, Lu HS, Zhang L, Chen LL, Gan MF
Asian Pacific journal of cancer prevention : APJCP 2014;15(13):5271-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(13):5271-6
MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis.
Cao XQ, Lu HS, Zhang L, Chen LL, Gan MF
Asian Pacific journal of cancer prevention : APJCP 2014;15(13):5271-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(13):5271-6
Detection of high levels of Survivin-immunoglobulin M immune complex in sera from hepatitis C virus infected patients with cirrhosis.
Matteucci C, Sorrentino R, Bellis L, Ettorre GM, Svicher V, Santoro R, Vennarecci G, Biasiolo A, Pontisso P, Scacciatelli D, Beneduce L, Sarrecchia C, Casalino P, Bernardini S, Pierimarchi P, Garaci E, Puoti C, Rasi G
Hepatology research : the official journal of the Japan Society of Hepatology 2014 Sep;44(9):1008-18
Hepatology research : the official journal of the Japan Society of Hepatology 2014 Sep;44(9):1008-18
AAG8 promotes carcinogenesis by activating STAT3.
Sun B, Kawahara M, Ehata S, Nagamune T
Cellular signalling 2014 Sep;26(9):1863-9
Cellular signalling 2014 Sep;26(9):1863-9
Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.
Cornago M, Garcia-Alberich C, Blasco-Angulo N, Vall-Llaura N, Nager M, Herreros J, Comella JX, Sanchis D, Llovera M
Cell death & disease 2014 Oct 2;5:e1435
Cell death & disease 2014 Oct 2;5:e1435
Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma.
Grazia G, Vegetti C, Benigni F, Penna I, Perotti V, Tassi E, Bersani I, Nicolini G, Canevari S, Carlo-Stella C, Gianni AM, Mortarini R, Anichini A
Cell death & disease 2014 Oct 2;5:e1434
Cell death & disease 2014 Oct 2;5:e1434
Prognostic utility of apoptosis index, Ki-67 and survivin expression in dogs with nasal carcinoma treated with orthovoltage radiation therapy.
Fu DR, Kato D, Watabe A, Endo Y, Kadosawa T
The Journal of veterinary medical science 2014 Nov;76(11):1505-12
The Journal of veterinary medical science 2014 Nov;76(11):1505-12
Prognostic utility of apoptosis index, Ki-67 and survivin expression in dogs with nasal carcinoma treated with orthovoltage radiation therapy.
Fu DR, Kato D, Watabe A, Endo Y, Kadosawa T
The Journal of veterinary medical science 2014 Nov;76(11):1505-12
The Journal of veterinary medical science 2014 Nov;76(11):1505-12
Ponatinib induces apoptosis in imatinib-resistant human mast cells by dephosphorylating mutant D816V KIT and silencing β-catenin signaling.
Jin B, Ding K, Pan J
Molecular cancer therapeutics 2014 May;13(5):1217-30
Molecular cancer therapeutics 2014 May;13(5):1217-30
The cellular inhibitor of apoptosis protein-2 is a possible target of novel treatment for endometriosis.
Taniguchi F, Higaki H, Izawa M, Azuma Y, Hirakawa E, Deura I, Iwabe T, Hata K, Harada T
American journal of reproductive immunology (New York, N.Y. : 1989) 2014 Mar;71(3):278-85
American journal of reproductive immunology (New York, N.Y. : 1989) 2014 Mar;71(3):278-85
The role of survivin in thyroid tumors: differences of expression in well-differentiated, non-well-differentiated, and anaplastic thyroid cancers.
Pannone G, Santoro A, Pasquali D, Zamparese R, Mattoni M, Russo G, Landriscina M, Piscazzi A, Toti P, Cignarelli M, Lo Muzio L, Bufo P
Thyroid : official journal of the American Thyroid Association 2014 Mar;24(3):511-9
Thyroid : official journal of the American Thyroid Association 2014 Mar;24(3):511-9
Early diagnostic value of survivin and its alternative splice variants in breast cancer.
Khan S, Bennit HF, Turay D, Perez M, Mirshahidi S, Yuan Y, Wall NR
BMC cancer 2014 Mar 12;14:176
BMC cancer 2014 Mar 12;14:176
Yin Yang 1 regulates the transcriptional repression of Survivin.
Galloway NR, Diaz Osterman CJ, Reiber K, Jutzy JM, Li F, Sui G, Soto U, Wall NR
Biochemical and biophysical research communications 2014 Feb 28;445(1):208-13
Biochemical and biophysical research communications 2014 Feb 28;445(1):208-13
Prognostic value of survivin and EGFR protein expression in triple-negative breast cancer (TNBC) patients.
Zhang M, Zhang X, Zhao S, Wang Y, Di W, Zhao G, Yang M, Zhang Q
Targeted oncology 2014 Dec;9(4):349-57
Targeted oncology 2014 Dec;9(4):349-57
The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.
Hori M, Miki T, Okamoto M, Yazama F, Konishi H, Kaneko H, Shimamoto F, Ota T, Temme A, Tatsuka M
PloS one 2013;8(2):e55710
PloS one 2013;8(2):e55710
Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST).
Alaggio R, Turrini R, Boldrin D, Merlo A, Gambini C, Ferrari A, Dall'igna P, Coffin CM, Martines A, Bonaldi L, De Salvo GL, Zanovello P, Rosato A
PloS one 2013;8(11):e80456
PloS one 2013;8(11):e80456
Inhibition of survivin influences the biological activities of canine histiocytic sarcoma cell lines.
Yamazaki H, Takagi S, Hoshino Y, Hosoya K, Okumura M
PloS one 2013;8(11):e79810
PloS one 2013;8(11):e79810
Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer.
Wang B, Zhao B, North P, Kong A, Huang J, Miao QR
PloS one 2013;8(11):e78083
PloS one 2013;8(11):e78083
IGF-IR promotes prostate cancer growth by stabilizing α5β1 integrin protein levels.
Sayeed A, Fedele C, Trerotola M, Ganguly KK, Languino LR
PloS one 2013;8(10):e76513
PloS one 2013;8(10):e76513
Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction.
Tyagi A, Raina K, Gangar S, Kaur M, Agarwal R, Agarwal C
Nutrition and cancer 2013;65 Suppl 1:44-53
Nutrition and cancer 2013;65 Suppl 1:44-53
Prognostic impact of human papillomavirus status, survivin, and epidermal growth factor receptor expression on survival in patients treated with radiochemotherapy for very advanced nonresectable oropharyngeal cancer.
Semrau R, Duerbaum H, Temming S, Huebbers C, Stenner M, Drebber U, Klussmann JP, Müller RP, Preuss SF
Head & neck 2013 Sep;35(9):1339-44
Head & neck 2013 Sep;35(9):1339-44
Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.
Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, Morandi P, Puviani M, Maiorana A, Roop DR, Pincelli C
International journal of molecular sciences 2013 Sep 26;14(10):19540-55
International journal of molecular sciences 2013 Sep 26;14(10):19540-55
The role of p21 Waf1/Cip1 in large airway epithelium in smokers with and without COPD.
Chiappara G, Gjomarkaj M, Virzì A, Sciarrino S, Ferraro M, Bruno A, Montalbano AM, Vitulo P, Minervini MI, Pipitone L, Pace E
Biochimica et biophysica acta 2013 Oct;1832(10):1473-81
Biochimica et biophysica acta 2013 Oct;1832(10):1473-81
Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells.
Honegger A, Leitz J, Bulkescher J, Hoppe-Seyler K, Hoppe-Seyler F
International journal of cancer 2013 Oct 1;133(7):1631-42
International journal of cancer 2013 Oct 1;133(7):1631-42
DNMT1: an emerging target in the treatment of invasive urinary bladder cancer.
Dhawan D, Ramos-Vara JA, Hahn NM, Waddell J, Olbricht GR, Zheng R, Stewart JC, Knapp DW
Urologic oncology 2013 Nov;31(8):1761-9
Urologic oncology 2013 Nov;31(8):1761-9
Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma.
Wang Z, Zheng Y, Park HJ, Li J, Carr JR, Chen YJ, Kiefer MM, Kopanja D, Bagchi S, Tyner AL, Raychaudhuri P
Molecular cancer therapeutics 2013 May;12(5):759-67
Molecular cancer therapeutics 2013 May;12(5):759-67
Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response.
Slagter-Jäger JG, Raney A, Lewis WE, Debenedette MA, Nicolette CA, Tcherepanova IY
Molecular therapy. Nucleic acids 2013 May 7;2:e91
Molecular therapy. Nucleic acids 2013 May 7;2:e91
PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin.
Cheng CW, Chow AK, Pang R, Fok EW, Kwong YL, Tse E
The American journal of pathology 2013 Mar;182(3):765-75
The American journal of pathology 2013 Mar;182(3):765-75
Enhanced inhibition of bladder cancer cell growth by simultaneous knockdown of antiapoptotic Bcl-xL and survivin in combination with chemotherapy.
Kunze D, Erdmann K, Froehner M, Wirth MP, Fuessel S
International journal of molecular sciences 2013 Jun 7;14(6):12297-312
International journal of molecular sciences 2013 Jun 7;14(6):12297-312
β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1.
Goel HL, Sayeed A, Breen M, Zarif MJ, Garlick DS, Leav I, Davis RJ, Fitzgerald TJ, Morrione A, Hsieh CC, Liu Q, Dicker AP, Altieri DC, Languino LR
Journal of cellular physiology 2013 Jul;228(7):1601-9
Journal of cellular physiology 2013 Jul;228(7):1601-9
Intratumoral concentration of estrogens and clinicopathological changes in ductal carcinoma in situ following aromatase inhibitor letrozole treatment.
Takagi K, Ishida T, Miki Y, Hirakawa H, Kakugawa Y, Amano G, Ebata A, Mori N, Nakamura Y, Watanabe M, Amari M, Ohuchi N, Sasano H, Suzuki T
British journal of cancer 2013 Jul 9;109(1):100-8
British journal of cancer 2013 Jul 9;109(1):100-8
Inhibition of STAT signalling in bladder cancer by diindolylmethane: relevance to cell adhesion, migration and proliferation.
Sun Y, Cheng MK, Griffiths TR, Mellon JK, Kai B, Kriajevska M, Manson MM
Current cancer drug targets 2013 Jan;13(1):57-68
Current cancer drug targets 2013 Jan;13(1):57-68
Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.
Gnana-Prakasam JP, Veeranan-Karmegam R, Coothankandaswamy V, Reddy SK, Martin PM, Thangaraju M, Smith SB, Ganapathy V
Investigative ophthalmology & visual science 2013 Jan 7;54(1):63-71
Investigative ophthalmology & visual science 2013 Jan 7;54(1):63-71
Functional characterization of novel mutations affecting survivin (BIRC5)-mediated therapy resistance in head and neck cancer patients.
Knauer SK, Unruhe B, Karczewski S, Hecht R, Fetz V, Bier C, Friedl S, Wollenberg B, Pries R, Habtemichael N, Heinrich UR, Stauber RH
Human mutation 2013 Feb;34(2):395-404
Human mutation 2013 Feb;34(2):395-404
Epithelial-to-mesenchymal transition: immunohistochemical investigation of related molecules in canine cutaneous epithelial tumours.
Bongiovanni L, D'Andrea A, Romanucci M, Malatesta D, Candolini M, Salda LD, Mechelli L, Sforna M, Brachelente C
Veterinary dermatology 2013 Feb;24(1):195-203.e42-3
Veterinary dermatology 2013 Feb;24(1):195-203.e42-3
Depletion of K-Ras promotes proteasome degradation of survivin.
Tecleab A, Sebti SM
Cell cycle (Georgetown, Tex.) 2013 Feb 1;12(3):522-32
Cell cycle (Georgetown, Tex.) 2013 Feb 1;12(3):522-32
HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.
Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, Hao X, Li Y, Qiao XT, Lin J, Fuchs J, Simeone DM, Chen ZN, Lawrence TS, Xu L
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Dec 15;19(24):6703-15
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Dec 15;19(24):6703-15
Suppression of actopaxin impairs hepatocellular carcinoma metastasis through modulation of cell migration and invasion.
Ng L, Tung-Ping Poon R, Yau S, Chow A, Lam C, Li HS, Chung-Cheung Yau T, Law WL, Pang R
Hepatology (Baltimore, Md.) 2013 Aug;58(2):667-79
Hepatology (Baltimore, Md.) 2013 Aug;58(2):667-79
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML).
Erba HP, Sayar H, Juckett M, Lahn M, Andre V, Callies S, Schmidt S, Kadam S, Brandt JT, Van Bockstaele D, Andreeff M
Investigational new drugs 2013 Aug;31(4):1023-34
Investigational new drugs 2013 Aug;31(4):1023-34
E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro.
Dallaglio K, Marconi A, Truzzi F, Lotti R, Palazzo E, Petrachi T, Saltari A, Coppini M, Pincelli C
Experimental dermatology 2013 Apr;22(4):255-61
Experimental dermatology 2013 Apr;22(4):255-61
Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress.
Kan CY, Petti C, Bracken L, Maritz M, Xu N, O'Brien R, Yang C, Liu T, Yuan J, Lock RB, MacKenzie KL
The Journal of biological chemistry 2013 Apr 26;288(17):12032-41
The Journal of biological chemistry 2013 Apr 26;288(17):12032-41
Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation.
Jacob NK, Cooley JV, Shirai K, Chakravarti A
OncoTargets and therapy 2012;5:7-20
OncoTargets and therapy 2012;5:7-20
Nutrient availability alters the effect of autophagy on sulindac sulfide-induced colon cancer cell apoptosis.
Chiou SK, Hoa N, Ge L, Jadus MR
Gastroenterology research and practice 2012;2012:897678
Gastroenterology research and practice 2012;2012:897678
Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma.
Chao C, Silverberg MJ, Martínez-Maza O, Chi M, Abrams DI, Haque R, Zha HD, McGuire M, Xu L, Said J
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Sep 1;18(17):4702-12
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Sep 1;18(17):4702-12
Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells.
Kunze D, Kraemer K, Erdmann K, Froehner M, Wirth MP, Fuessel S
International journal of oncology 2012 Oct;41(4):1271-7
International journal of oncology 2012 Oct;41(4):1271-7
Nuclear survivin expression as a potentially useful tool for the diagnosis of canine cutaneous sebaceous lesions.
Bongiovanni L, Suter MM, Malatesta D, Ordinelli A, Ciccarelli A, Romanucci M, Brenner O, Della Salda L
Veterinary dermatology 2012 Oct;23(5):394-e73
Veterinary dermatology 2012 Oct;23(5):394-e73
Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease.
de Souza HS, West GA, Rebert N, de la Motte C, Drazba J, Fiocchi C
Gastroenterology 2012 Oct;143(4):1017-26.e9
Gastroenterology 2012 Oct;143(4):1017-26.e9
Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.
Wang F, Ulyanova NP, Daum JR, Patnaik D, Kateneva AV, Gorbsky GJ, Higgins JM
The Journal of cell biology 2012 Oct 15;199(2):251-68
The Journal of cell biology 2012 Oct 15;199(2):251-68
Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.
Min L, Ji Y, Bakiri L, Qiu Z, Cen J, Chen X, Chen L, Scheuch H, Zheng H, Qin L, Zatloukal K, Hui L, Wagner EF
Nature cell biology 2012 Nov;14(11):1203-11
Nature cell biology 2012 Nov;14(11):1203-11
Accumulation of α-synuclein triggered by presynaptic dysfunction.
Nakata Y, Yasuda T, Fukaya M, Yamamori S, Itakura M, Nihira T, Hayakawa H, Kawanami A, Kataoka M, Nagai M, Sakagami H, Takahashi M, Mizuno Y, Mochizuki H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 28;32(48):17186-96
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Nov 28;32(48):17186-96
Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer.
Tuncel H, Shimamoto F, Kaneko Guangying Qi H, Aoki E, Jikihara H, Nakai S, Takata T, Tatsuka M
Oncology letters 2012 May;3(5):1109-1114
Oncology letters 2012 May;3(5):1109-1114
PSA regulates androgen receptor expression in prostate cancer cells.
Saxena P, Trerotola M, Wang T, Li J, Sayeed A, Vanoudenhove J, Adams DS, Fitzgerald TJ, Altieri DC, Languino LR
The Prostate 2012 May 15;72(7):769-76
The Prostate 2012 May 15;72(7):769-76
Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells.
Francisco R, Pérez-Perarnau A, Cortés C, Gil J, Tauler A, Ambrosio S
Cancer letters 2012 May 1;318(1):42-52
Cancer letters 2012 May 1;318(1):42-52
Total Survivin and acetylated Survivin correlate with distinct molecular subtypes of breast cancer.
Yakirevich E, Samkari A, Holloway MP, Lu S, Singh K, Yu J, Fenton MA, Altura RA
Human pathology 2012 Jun;43(6):865-73
Human pathology 2012 Jun;43(6):865-73
Targeting X-linked inhibitor of apoptosis protein inhibits pancreatic cancer cell growth through p-Akt depletion.
Jiang C, Yi XP, Shen H, Li YX
World journal of gastroenterology 2012 Jun 21;18(23):2956-65
World journal of gastroenterology 2012 Jun 21;18(23):2956-65
Immunohistochemical investigation of cell cycle and apoptosis regulators (survivin, β-catenin, p53, caspase 3) in canine appendicular osteosarcoma.
Bongiovanni L, Mazzocchetti F, Malatesta D, Romanucci M, Ciccarelli A, Buracco P, De Maria R, Palmieri C, Martano M, Morello E, Maniscalco L, Della Salda L
BMC veterinary research 2012 Jun 11;8:78
BMC veterinary research 2012 Jun 11;8:78
Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification.
Okamoto W, Okamoto I, Arao T, Kuwata K, Hatashita E, Yamaguchi H, Sakai K, Yanagihara K, Nishio K, Nakagawa K
Molecular cancer therapeutics 2012 Jul;11(7):1557-64
Molecular cancer therapeutics 2012 Jul;11(7):1557-64
Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction.
Chen B, Yuping S, Ni J
Molecular biology reports 2012 Jan;39(1):185-91
Molecular biology reports 2012 Jan;39(1):185-91
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.
Stauber RH, Knauer SK, Habtemichael N, Bier C, Unruhe B, Weisheit S, Spange S, Nonnenmacher F, Fetz V, Ginter T, Reichardt S, Liebmann C, Schneider G, Krämer OH
Oncotarget 2012 Jan;3(1):31-43
Oncotarget 2012 Jan;3(1):31-43
Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients.
Finkelstein SE, Iclozan C, Bui MM, Cotter MJ, Ramakrishnan R, Ahmed J, Noyes DR, Cheong D, Gonzalez RJ, Heysek RV, Berman C, Lenox BC, Janssen W, Zager JS, Sondak VK, Letson GD, Antonia SJ, Gabrilovich DI
International journal of radiation oncology, biology, physics 2012 Feb 1;82(2):924-32
International journal of radiation oncology, biology, physics 2012 Feb 1;82(2):924-32
Oestrogen-induced genes in ductal carcinoma in situ: their comparison with invasive ductal carcinoma.
Ebata A, Suzuki T, Takagi K, Miki Y, Onodera Y, Nakamura Y, Fujishima F, Ishida K, Watanabe M, Tamaki K, Ishida T, Ohuchi N, Sasano H
Endocrine-related cancer 2012 Aug;19(4):485-96
Endocrine-related cancer 2012 Aug;19(4):485-96
Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models.
Kavitha CV, Agarwal C, Agarwal R, Deep G
PloS one 2011;6(8):e22745
PloS one 2011;6(8):e22745
The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells.
Lechler P, Schaumburger J, Köck FX, Balakrishnan S, Doukas S, Prantl L, Grifka J
Calcified tissue international 2011 Sep;89(3):211-20
Calcified tissue international 2011 Sep;89(3):211-20
Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain.
Page BD, Fletcher S, Yue P, Li Z, Zhang X, Sharmeen S, Datti A, Wrana JL, Trudel S, Schimmer AD, Turkson J, Gunning PT
Bioorganic & medicinal chemistry letters 2011 Sep 15;21(18):5605-9
Bioorganic & medicinal chemistry letters 2011 Sep 15;21(18):5605-9
Expression of HuR, COX-2, and survivin in lung cancers; cytoplasmic HuR stabilizes cyclooxygenase-2 in squamous cell carcinomas.
Kim GY, Lim SJ, Kim YW
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011 Oct;24(10):1336-47
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011 Oct;24(10):1336-47
Pigmented spindle cell nevus: clues for differentiating it from spindle cell malignant melanoma. A comprehensive survey including clinicopathologic, immunohistochemical, and FISH studies.
Díaz A, Valera A, Carrera C, Hakim S, Aguilera P, García A, Palou J, Puig S, Malvehy J, Alos L
The American journal of surgical pathology 2011 Nov;35(11):1733-42
The American journal of surgical pathology 2011 Nov;35(11):1733-42
Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients.
Felisiak-Golabek A, Rembiszewska A, Rzepecka IK, Szafron L, Madry R, Murawska M, Napiorkowski T, Sobiczewski P, Osuch B, Kupryjanczyk J, Polish Ovarian Cancer Study Group (POCSG).
Journal of ovarian research 2011 Nov 10;4(1):20
Journal of ovarian research 2011 Nov 10;4(1):20
Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
El Ghamrasni S, Pamidi A, Halaby MJ, Bohgaki M, Cardoso R, Li L, Venkatesan S, Sethu S, Hirao A, Mak TW, Hande MP, Hakem A, Hakem R
PLoS genetics 2011 May;7(5):e1001385
PLoS genetics 2011 May;7(5):e1001385
Russia pledges $4 billion for Pharma-2020 plan.
Peach G
Nature medicine 2011 May;17(5):517
Nature medicine 2011 May;17(5):517
STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma.
Scuto A, Kujawski M, Kowolik C, Krymskaya L, Wang L, Weiss LM, Digiusto D, Yu H, Forman S, Jove R
Cancer research 2011 May 1;71(9):3182-8
Cancer research 2011 May 1;71(9):3182-8
The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines.
Fossey SL, Bear MD, Lin J, Li C, Schwartz EB, Li PK, Fuchs JR, Fenger J, Kisseberth WC, London CA
BMC cancer 2011 Mar 28;11:112
BMC cancer 2011 Mar 28;11:112
Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
Emmanuel C, Gava N, Kennedy C, Balleine RL, Sharma R, Wain G, Brand A, Hogg R, Etemadmoghadam D, George J, Australian Ovarian Cancer Study Group, Birrer MJ, Clarke CL, Chenevix-Trench G, Bowtell DD, Harnett PR, deFazio A
PloS one 2011 Mar 15;6(3):e17617
PloS one 2011 Mar 15;6(3):e17617
The prostaglandin E2 receptor, EP2, regulates survivin expression via an EGFR/STAT3 pathway in UVB-exposed mouse skin.
Chun KS, Langenbach R
Molecular carcinogenesis 2011 Jun;50(6):439-48
Molecular carcinogenesis 2011 Jun;50(6):439-48
Garlic constituent diallyl trisulfide suppresses x-linked inhibitor of apoptosis protein in prostate cancer cells in culture and in vivo.
Kim SH, Bommareddy A, Singh SV
Cancer prevention research (Philadelphia, Pa.) 2011 Jun;4(6):897-906
Cancer prevention research (Philadelphia, Pa.) 2011 Jun;4(6):897-906
Sulindac sulfide induces autophagic death in gastric epithelial cells via survivin down-regulation: a mechanism of NSAIDs-induced gastric injury.
Chiou SK, Hoa N, Hodges A
Biochemical pharmacology 2011 Jun 1;81(11):1317-23
Biochemical pharmacology 2011 Jun 1;81(11):1317-23
The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro.
Lechler P, Balakrishnan S, Schaumburger J, Grässel S, Baier C, Grifka J, Straub RH, Renkawitz T
BMC musculoskeletal disorders 2011 Jul 5;12:150
BMC musculoskeletal disorders 2011 Jul 5;12:150
Survivin is released from cancer cells via exosomes.
Khan S, Jutzy JM, Aspe JR, McGregor DW, Neidigh JW, Wall NR
Apoptosis : an international journal on programmed cell death 2011 Jan;16(1):1-12
Apoptosis : an international journal on programmed cell death 2011 Jan;16(1):1-12
p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation.
Xia M, Knezevic D, Vassilev LT
Oncogene 2011 Jan 20;30(3):346-55
Oncogene 2011 Jan 20;30(3):346-55
Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles.
El-Maarri O, Walier M, Behne F, van Üüm J, Singer H, Diaz-Lacava A, Nüsgen N, Niemann B, Watzka M, Reinsberg J, van der Ven H, Wienker T, Stoffel-Wagner B, Schwaab R, Oldenburg J
PloS one 2011 Jan 19;6(1):e16252
PloS one 2011 Jan 19;6(1):e16252
Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.
AbouAlaiwi WA, Ratnam S, Booth RL, Shah JV, Nauli SM
Human molecular genetics 2011 Jan 15;20(2):354-67
Human molecular genetics 2011 Jan 15;20(2):354-67
Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.
Wei W, Chua MS, Grepper S, So SK
Molecular cancer 2011 Feb 11;10:16
Molecular cancer 2011 Feb 11;10:16
The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro.
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, Schaumburger J
BMC cancer 2011 Apr 2;11:120
BMC cancer 2011 Apr 2;11:120
Concomitant expression of HER2 and HIF-1alpha is a predictor of poor prognosis in uterine cervical carcinoma treated with concurrent chemoradiotherapy: prospective analysis (KGROG0501).
Niibe Y, Watanabe J, Tsunoda S, Arai M, Arai T, Kawaguchi M, Matsuo K, Jobo T, Ono S, Numata A, Unno N, Hayakawa K
European journal of gynaecological oncology 2010;31(5):491-6
European journal of gynaecological oncology 2010;31(5):491-6
Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules.
Velmurugan B, Gangar SC, Kaur M, Tyagi A, Deep G, Agarwal R
Pharmaceutical research 2010 Oct;27(10):2085-97
Pharmaceutical research 2010 Oct;27(10):2085-97
Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear.
Habtemichael N, Heinrich UR, Knauer SK, Schmidtmann I, Bier C, Docter D, Brochhausen C, Helling K, Brieger J, Stauber RH, Mann WJ
Molecular and cellular neurosciences 2010 Nov;45(3):297-305
Molecular and cellular neurosciences 2010 Nov;45(3):297-305
BRCA1-IRIS overexpression promotes cisplatin resistance in ovarian cancer cells.
Chock KL, Allison JM, Shimizu Y, ElShamy WM
Cancer research 2010 Nov 1;70(21):8782-91
Cancer research 2010 Nov 1;70(21):8782-91
Immunohistochemical detection of survivin in canine lymphoma.
Wimmershoff J, Polkinghorne A, Grest P, Schade B, Marchal T, Keller SM, Guscetti F
Journal of comparative pathology 2010 May;142(4):311-22
Journal of comparative pathology 2010 May;142(4):311-22
Integrative genome comparison of primary and metastatic melanomas.
Kabbarah O, Nogueira C, Feng B, Nazarian RM, Bosenberg M, Wu M, Scott KL, Kwong LN, Xiao Y, Cordon-Cardo C, Granter SR, Ramaswamy S, Golub T, Duncan LM, Wagner SN, Brennan C, Chin L
PloS one 2010 May 24;5(5):e10770
PloS one 2010 May 24;5(5):e10770
Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.
Lee S, Donehower LA, Herron AJ, Moore DD, Fu L
PloS one 2010 Jun 7;5(6):e10995
PloS one 2010 Jun 7;5(6):e10995
Detection of autoantibodies against survivin in sera from cancer dogs.
Tango Y, Kano R, Maruyama H, Asano K, Tanaka S, Hasegawa A, Kamata H
The Journal of veterinary medical science 2010 Jul;72(7):917-20
The Journal of veterinary medical science 2010 Jul;72(7):917-20
Detection of autoantibodies against survivin in sera from cancer dogs.
Tango Y, Kano R, Maruyama H, Asano K, Tanaka S, Hasegawa A, Kamata H
The Journal of veterinary medical science 2010 Jul;72(7):917-20
The Journal of veterinary medical science 2010 Jul;72(7):917-20
Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia.
Svec J, Musílková J, Bryndová J, Jirásek T, Mandys V, Kment M, Pácha J
Inflammatory bowel diseases 2010 Jul;16(7):1127-37
Inflammatory bowel diseases 2010 Jul;16(7):1127-37
Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis.
Rückert F, Samm N, Lehner AK, Saeger HD, Grützmann R, Pilarsky C
BMC cancer 2010 Jul 20;10:379
BMC cancer 2010 Jul 20;10:379
An otoprotective role for the apoptosis inhibitor protein survivin.
Knauer SK, Heinrich UR, Bier C, Habtemichael N, Docter D, Helling K, Mann WJ, Stauber RH
Cell death & disease 2010 Jul 1;1:e51
Cell death & disease 2010 Jul 1;1:e51
A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC.
Dean EJ, Ward T, Pinilla C, Houghten R, Welsh K, Makin G, Ranson M, Dive C
British journal of cancer 2010 Jan 5;102(1):97-103
British journal of cancer 2010 Jan 5;102(1):97-103
Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells.
López-Royuela N, Balsas P, Galán-Malo P, Anel A, Marzo I, Naval J
Biochimica et biophysica acta 2010 Feb;1803(2):311-22
Biochimica et biophysica acta 2010 Feb;1803(2):311-22
Differential regulation of TP73 isoforms by 1α,25-dihydroxyvitamin D3 and survivin in human colon and breast carcinomas.
Díaz R, González-Sancho JM, Soldevilla B, Silva J, García JM, García V, Peña C, Herrera M, Gómez I, Bonilla F, Domínguez G
Genes, chromosomes & cancer 2010 Dec;49(12):1135-42
Genes, chromosomes & cancer 2010 Dec;49(12):1135-42
Tumor survivin is downregulated by the antisense oligonucleotide LY2181308: a proof-of-concept, first-in-human dose study.
Talbot DC, Ranson M, Davies J, Lahn M, Callies S, André V, Kadam S, Burgess M, Slapak C, Olsen AL, McHugh PJ, de Bono JS, Matthews J, Saleem A, Price P
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Dec 15;16(24):6150-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Dec 15;16(24):6150-8
Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin.
Habtemichael N, Wünsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, Heinrich UR, Mann WJ, Stauber RH, Knauer SK
Gene 2010 Dec 1;469(1-2):9-17
Gene 2010 Dec 1;469(1-2):9-17
Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice.
Weber A, Boger R, Vick B, Urbanik T, Haybaeck J, Zoller S, Teufel A, Krammer PH, Opferman JT, Galle PR, Schuchmann M, Heikenwalder M, Schulze-Bergkamen H
Hepatology (Baltimore, Md.) 2010 Apr;51(4):1226-36
Hepatology (Baltimore, Md.) 2010 Apr;51(4):1226-36
Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B.
Qi G, Kudo Y, Ando T, Tsunematsu T, Shimizu N, Siriwardena SB, Yoshida M, Keikhaee MR, Ogawa I, Takata T
Oral oncology 2010 Apr;46(4):263-70
Oral oncology 2010 Apr;46(4):263-70
Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice.
Lou Y, Peng Q, Nolan B, Wagner GC, Lu Y
Carcinogenesis 2010 Apr;31(4):671-8
Carcinogenesis 2010 Apr;31(4):671-8
Relationship between the expression of cyclooxygenase-2 and survivin in primary pterygium.
Maxia C, Perra MT, Demurtas P, Minerba L, Murtas D, Piras F, Cabrera R, Ribatti D, Sirigu P
Molecular vision 2009;15:458-63
Molecular vision 2009;15:458-63
Survival responses of human embryonic stem cells to DNA damage.
Filion TM, Qiao M, Ghule PN, Mandeville M, van Wijnen AJ, Stein JL, Lian JB, Altieri DC, Stein GS
Journal of cellular physiology 2009 Sep;220(3):586-92
Journal of cellular physiology 2009 Sep;220(3):586-92
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, Okamoto M, Tatsuka M, Nakai S, Shimamoto F
Oncology reports 2009 Sep;22(3):557-62
Oncology reports 2009 Sep;22(3):557-62
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, Okamoto M, Tatsuka M, Nakai S, Shimamoto F
Oncology reports 2009 Sep;22(3):557-62
Oncology reports 2009 Sep;22(3):557-62
Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells.
Wei W, Chua MS, Grepper S, So SK
Molecular cancer 2009 Sep 24;8:76
Molecular cancer 2009 Sep 24;8:76
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.
Eberhard Y, McDermott SP, Wang X, Gronda M, Venugopal A, Wood TE, Hurren R, Datti A, Batey RA, Wrana J, Antholine WE, Dick JE, Schimmer AD
Blood 2009 Oct 1;114(14):3064-73
Blood 2009 Oct 1;114(14):3064-73
TNFR2-deficient memory CD8 T cells provide superior protection against tumor cell growth.
Kim EY, Teh SJ, Yang J, Chow MT, Teh HS
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 15;183(10):6051-7
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 15;183(10):6051-7
Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study.
Shariat SF, Karakiewicz PI, Godoy G, Karam JA, Ashfaq R, Fradet Y, Isbarn H, Montorsi F, Jeldres C, Bastian PJ, Nielsen ME, Müller SC, Sagalowsky AI, Lotan Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Nov 15;15(22):7012-9
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Nov 15;15(22):7012-9
Expression of the antiapoptosis gene Survivin predicts poor prognosis of stage III gastric adenocarcinoma.
Song KY, Jung CK, Park WS, Park CH
Japanese journal of clinical oncology 2009 May;39(5):290-6
Japanese journal of clinical oncology 2009 May;39(5):290-6
Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin.
Fetz V, Bier C, Habtemichael N, Schuon R, Schweitzer A, Kunkel M, Engels K, Kovács AF, Schneider S, Mann W, Stauber RH, Knauer SK
International journal of cancer 2009 May 1;124(9):2033-41
International journal of cancer 2009 May 1;124(9):2033-41
Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells.
Allison SJ, Jiang M, Milner J
Aging 2009 Mar 2;1(3):316-27
Aging 2009 Mar 2;1(3):316-27
ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence.
Jia L, Soengas MS, Sun Y
Cancer research 2009 Jun 15;69(12):4974-82
Cancer research 2009 Jun 15;69(12):4974-82
Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.
Guha M, Plescia J, Leav I, Li J, Languino LR, Altieri DC
Cancer research 2009 Jun 15;69(12):4954-8
Cancer research 2009 Jun 15;69(12):4954-8
Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.
Yuan J, Yang BM, Zhong ZH, Shats I, Milyavsky M, Rotter V, Lock RB, Reddel RR, MacKenzie KL
Oncogene 2009 Jul 23;28(29):2678-89
Oncogene 2009 Jul 23;28(29):2678-89
Seliciclib (CYC202, R-roscovitine) enhances the antitumor effect of doxorubicin in vivo in a breast cancer xenograft model.
Appleyard MV, O'Neill MA, Murray KE, Paulin FE, Bray SE, Kernohan NM, Levison DA, Lane DP, Thompson AM
International journal of cancer 2009 Jan 15;124(2):465-72
International journal of cancer 2009 Jan 15;124(2):465-72
Impaired insulin-mediated vasorelaxation in diabetic Goto-Kakizaki rats is caused by impaired Akt phosphorylation.
Lee JH, Palaia T, Ragolia L
American journal of physiology. Cell physiology 2009 Feb;296(2):C327-38
American journal of physiology. Cell physiology 2009 Feb;296(2):C327-38
Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance.
Lu J, Tan M, Huang WC, Li P, Guo H, Tseng LM, Su XH, Yang WT, Treekitkarnmongkol W, Andreeff M, Symmans F, Yu D
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Feb 15;15(4):1326-34
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Feb 15;15(4):1326-34
Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity.
Adler M, Müller K, Rached E, Dekant W, Mally A
Carcinogenesis 2009 Apr;30(4):711-9
Carcinogenesis 2009 Apr;30(4):711-9
Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferation.
Baba HA, Wohlschlaeger J, Schmitz KJ, Nadalin S, Lang H, Benesch A, Gu Y, Biglarnia AR, Sotiropoulos GC, Takeda A, Takeda N, von Wnuck Lipinski K, Levkau B
Liver international : official journal of the International Association for the Study of the Liver 2009 Apr;29(4):585-92
Liver international : official journal of the International Association for the Study of the Liver 2009 Apr;29(4):585-92
Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential.
Khan S, Aspe JR, Asumen MG, Almaguel F, Odumosu O, Acevedo-Martinez S, De Leon M, Langridge WH, Wall NR
British journal of cancer 2009 Apr 7;100(7):1073-86
British journal of cancer 2009 Apr 7;100(7):1073-86
Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.
Augello C, Caruso L, Maggioni M, Donadon M, Montorsi M, Santambrogio R, Torzilli G, Vaira V, Pellegrini C, Roncalli M, Coggi G, Bosari S
BMC cancer 2009 Apr 27;9:125
BMC cancer 2009 Apr 27;9:125
Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis.
Gould Rothberg BE, Bracken MB, Rimm DL
Journal of the National Cancer Institute 2009 Apr 1;101(7):452-74
Journal of the National Cancer Institute 2009 Apr 1;101(7):452-74
Fas-mediated killing of primary prostate cancer cells is increased by mitoxantrone and docetaxel.
Symes JC, Kurin M, Fleshner NE, Medin JA
Molecular cancer therapeutics 2008 Sep;7(9):3018-28
Molecular cancer therapeutics 2008 Sep;7(9):3018-28
A survivin-ran complex regulates spindle formation in tumor cells.
Xia F, Canovas PM, Guadagno TM, Altieri DC
Molecular and cellular biology 2008 Sep;28(17):5299-311
Molecular and cellular biology 2008 Sep;28(17):5299-311
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.
Wang RH, Sengupta K, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, Jia R, Zheng ZM, Appella E, Wang XW, Ried T, Deng CX
Cancer cell 2008 Oct 7;14(4):312-23
Cancer cell 2008 Oct 7;14(4):312-23
BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis.
Seo SI, Gera L, Zhau HE, Qian WP, Iqbal S, Johnson NA, Zhang S, Zayzafoon M, Stewart J, Wang R, Chung LW, Wu D
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Oct 1;14(19):6198-206
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Oct 1;14(19):6198-206
AML1/ETO-induced survivin expression inhibits transcriptional regulation of myeloid differentiation.
Balkhi MY, Christopeit M, Chen Y, Geletu M, Behre G
Experimental hematology 2008 Nov;36(11):1449-60
Experimental hematology 2008 Nov;36(11):1449-60
Antisense-mediated inhibition of survivin, hTERT and VEGF in bladder cancer cells in vitro and in vivo.
Kunze D, Wuttig D, Kausch I, Blietz C, Blumhoff L, Burmeister Y, Kraemer K, Fuessel S, Toma M, Schwenzer B, Meye A, Grimm MO, Hakenberg OW, Jocham D, Wirth MP
International journal of oncology 2008 May;32(5):1049-56
International journal of oncology 2008 May;32(5):1049-56
Neoadjuvant docetaxel and capecitabine in patients with high risk prostate cancer.
Friedman J, Dunn RL, Wood D, Vaishampayan U, Wu A, Bradley D, Montie J, Sarkar FH, Shah RB, Hussain M
The Journal of urology 2008 Mar;179(3):911-5; discussion 915-6
The Journal of urology 2008 Mar;179(3):911-5; discussion 915-6
Tumor cell dependence on Ran-GTP-directed mitosis.
Xia F, Lee CW, Altieri DC
Cancer research 2008 Mar 15;68(6):1826-33
Cancer research 2008 Mar 15;68(6):1826-33
Expression of the inhibitor of apoptosis protein family in multiple sclerosis reveals a potential immunomodulatory role during autoimmune mediated demyelination.
Hebb AL, Moore CS, Bhan V, Campbell T, Fisk JD, Robertson HA, Thorne M, Lacasse E, Holcik M, Gillard J, Crocker SJ, Robertson GS
Multiple sclerosis (Houndmills, Basingstoke, England) 2008 Jun;14(5):577-94
Multiple sclerosis (Houndmills, Basingstoke, England) 2008 Jun;14(5):577-94
Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis.
Lee CW, Raskett CM, Prudovsky I, Altieri DC
Cancer research 2008 Jul 1;68(13):5273-81
Cancer research 2008 Jul 1;68(13):5273-81
NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas.
Engels K, Knauer SK, Loibl S, Fetz V, Harter P, Schweitzer A, Fisseler-Eckhoff A, Kommoss F, Hanker L, Nekljudova V, Hermanns I, Kleinert H, Mann W, du Bois A, Stauber RH
Cancer research 2008 Jul 1;68(13):5159-66
Cancer research 2008 Jul 1;68(13):5159-66
pp32/PHAPI determines the apoptosis response of non-small-cell lung cancer.
Hoffarth S, Zitzer A, Wiewrodt R, Hähnel PS, Beyer V, Kreft A, Biesterfeld S, Schuler M
Cell death and differentiation 2008 Jan;15(1):161-70
Cell death and differentiation 2008 Jan;15(1):161-70
Survivin expression in glioblastomas correlates with proliferation, but not with apoptosis.
Mellai M, Caldera V, Patrucco A, Annovazzi L, Schiffer D
Anticancer research 2008 Jan-Feb;28(1A):109-18
Anticancer research 2008 Jan-Feb;28(1A):109-18
Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
Singh RP, Tyagi A, Sharma G, Mohan S, Agarwal R
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jan 1;14(1):300-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jan 1;14(1):300-8
Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibition.
Borghouts C, Kunz C, Delis N, Groner B
Molecular cancer research : MCR 2008 Feb;6(2):267-81
Molecular cancer research : MCR 2008 Feb;6(2):267-81
Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure.
Kindt N, Menzebach A, Van de Wouwer M, Betz I, De Vriese A, Conway EM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Feb;22(2):510-21
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Feb;22(2):510-21
Nuclear survivin has reduced stability and is not cytoprotective.
Connell CM, Colnaghi R, Wheatley SP
The Journal of biological chemistry 2008 Feb 8;283(6):3289-96
The Journal of biological chemistry 2008 Feb 8;283(6):3289-96
Hsp60 regulation of tumor cell apoptosis.
Ghosh JC, Dohi T, Kang BH, Altieri DC
The Journal of biological chemistry 2008 Feb 22;283(8):5188-94
The Journal of biological chemistry 2008 Feb 22;283(8):5188-94
Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia.
Zhang L, Murray F, Zahno A, Kanter JR, Chou D, Suda R, Fenlon M, Rassenti L, Cottam H, Kipps TJ, Insel PA
Proceedings of the National Academy of Sciences of the United States of America 2008 Dec 9;105(49):19532-7
Proceedings of the National Academy of Sciences of the United States of America 2008 Dec 9;105(49):19532-7
Imatinib targeting of KIT-mutant oncoprotein in melanoma.
Jiang X, Zhou J, Yuen NK, Corless CL, Heinrich MC, Fletcher JA, Demetri GD, Widlund HR, Fisher DE, Hodi FS
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Dec 1;14(23):7726-32
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Dec 1;14(23):7726-32
Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis.
Dai Y, Liu M, Tang W, DeSano J, Burstein E, Davis M, Pienta K, Lawrence T, Xu L
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Dec 1;14(23):7701-10
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Dec 1;14(23):7701-10
Adeno-sh-beta-catenin abolishes ischemic preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2, and survivin in ischemic rat myocardium.
Thirunavukkarasu M, Han Z, Zhan L, Penumathsa SV, Menon VP, Maulik N
Antioxidants & redox signaling 2008 Aug;10(8):1475-84
Antioxidants & redox signaling 2008 Aug;10(8):1475-84
T-cell responses to survivin in cancer patients undergoing radiation therapy.
Schaue D, Comin-Anduix B, Ribas A, Zhang L, Goodglick L, Sayre JW, Debucquoy A, Haustermans K, McBride WH
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Aug 1;14(15):4883-90
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Aug 1;14(15):4883-90
Attenuation of apoptosis by chromogranin A-induced Akt and survivin pathways in prostate cancer cells.
Gong J, Lee J, Akio H, Schlegel PN, Shen R
Endocrinology 2007 Sep;148(9):4489-99
Endocrinology 2007 Sep;148(9):4489-99
Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40.
Niedbala W, Cai B, Liu H, Pitman N, Chang L, Liew FY
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 25;104(39):15478-83
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 25;104(39):15478-83
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.
Moiseeva EP, Almeida GM, Jones GD, Manson MM
Molecular cancer therapeutics 2007 Nov;6(11):3071-9
Molecular cancer therapeutics 2007 Nov;6(11):3071-9
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, Klanke B, Weidemann A, Warnecke C, Amann K, Engehausen D, Willam C, Eckardt KU, Rödel F, Wiesener MS
The American journal of pathology 2007 Nov;171(5):1483-98
The American journal of pathology 2007 Nov;171(5):1483-98
Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed.
Skoufias DA, Indorato RL, Lacroix F, Panopoulos A, Margolis RL
The Journal of cell biology 2007 Nov 19;179(4):671-85
The Journal of cell biology 2007 Nov 19;179(4):671-85
Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments.
Huang H, Feng J, Famulski J, Rattner JB, Liu ST, Kao GD, Muschel R, Chan GK, Yen TJ
The Journal of cell biology 2007 May 7;177(3):413-24
The Journal of cell biology 2007 May 7;177(3):413-24
Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder.
Margulis V, Shariat SF, Ashfaq R, Thompson M, Sagalowsky AI, Hsieh JT, Lotan Y
The Journal of urology 2007 Mar;177(3):1163-8
The Journal of urology 2007 Mar;177(3):1163-8
Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition?
Wuttig D, Kunze D, Fuessel S, Toma M, Stade J, Kotzsch M, Kappler M, Taubert H, Schwenzer B, Baretton G, Hakenberg OW, Meye A, Wirth MP
International journal of oncology 2007 Jun;30(6):1317-24
International journal of oncology 2007 Jun;30(6):1317-24
Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition?
Wuttig D, Kunze D, Fuessel S, Toma M, Stade J, Kotzsch M, Kappler M, Taubert H, Schwenzer B, Baretton G, Hakenberg OW, Meye A, Wirth MP
International journal of oncology 2007 Jun;30(6):1317-24
International journal of oncology 2007 Jun;30(6):1317-24
Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.
Deep G, Oberlies NH, Kroll DJ, Agarwal R
Carcinogenesis 2007 Jul;28(7):1533-42
Carcinogenesis 2007 Jul;28(7):1533-42
Autoantibodies to the inhibitor of apoptosis protein survivin in patients with brain tumors.
Söling A, Plugge EM, Schmitz M, Weigle B, Jacob R, Illert J, Holzhausen HJ, Rainov NG
International journal of oncology 2007 Jan;30(1):123-8
International journal of oncology 2007 Jan;30(1):123-8
Nuclear export is essential for the tumor-promoting activity of survivin.
Knauer SK, Krämer OH, Knösel T, Engels K, Rödel F, Kovács AF, Dietmaier W, Klein-Hitpass L, Habtemichael N, Schweitzer A, Brieger J, Rödel C, Mann W, Petersen I, Heinzel T, Stauber RH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Jan;21(1):207-16
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Jan;21(1):207-16
Formin-2 is required for spindle migration and for the late steps of cytokinesis in mouse oocytes.
Dumont J, Million K, Sunderland K, Rassinier P, Lim H, Leader B, Verlhac MH
Developmental biology 2007 Jan 1;301(1):254-65
Developmental biology 2007 Jan 1;301(1):254-65
Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis.
Caldas H, Fangusaro JR, Boué DR, Holloway MP, Altura RA
Blood 2007 Feb 15;109(4):1479-89
Blood 2007 Feb 15;109(4):1479-89
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
Tyagi A, Raina K, Singh RP, Gu M, Agarwal C, Harrison G, Glode LM, Agarwal R
Molecular cancer therapeutics 2007 Dec;6(12 Pt 1):3248-55
Molecular cancer therapeutics 2007 Dec;6(12 Pt 1):3248-55
Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies.
Vischioni B, Oudejans JJ, Kruyt FA, Giaccone G, Rodriguez JA
Histopathology 2007 Apr;50(5):671-5
Histopathology 2007 Apr;50(5):671-5
Dynamic intracellular survivin in oral squamous cell carcinoma: underlying molecular mechanism and potential as an early prognostic marker.
Engels K, Knauer SK, Metzler D, Simf C, Struschka O, Bier C, Mann W, Kovács AF, Stauber RH
The Journal of pathology 2007 Apr;211(5):532-40
The Journal of pathology 2007 Apr;211(5):532-40
Beta-catenin overexpression reduces myocardial infarct size through differential effects on cardiomyocytes and cardiac fibroblasts.
Hahn JY, Cho HJ, Bae JW, Yuk HS, Kim KI, Park KW, Koo BK, Chae IH, Shin CS, Oh BH, Choi YS, Park YB, Kim HS
The Journal of biological chemistry 2006 Oct 13;281(41):30979-89
The Journal of biological chemistry 2006 Oct 13;281(41):30979-89
Prognostic significance of the Epstein-Barr virus, p53, Bcl-2, and survivin in nasopharyngeal cancer.
Yip KW, Shi W, Pintilie M, Martin JD, Mocanu JD, Wong D, MacMillan C, Gullane P, O'Sullivan B, Bastianutto C, Liu FF
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Oct 1;12(19):5726-32
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Oct 1;12(19):5726-32
Nucleocytoplasmic shuttling and the biological activity of mouse survivin are regulated by an active nuclear export signal.
Stauber RH, Rabenhorst U, Rekik A, Engels K, Bier C, Knauer SK
Traffic (Copenhagen, Denmark) 2006 Nov;7(11):1461-72
Traffic (Copenhagen, Denmark) 2006 Nov;7(11):1461-72
Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients.
Vischioni B, Oudejans JJ, Vos W, Rodriguez JA, Giaccone G
Molecular cancer therapeutics 2006 Nov;5(11):2905-13
Molecular cancer therapeutics 2006 Nov;5(11):2905-13
Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
Robles AI, Wright MH, Gandhi B, Feis SS, Hanigan CL, Wiestner A, Varticovski L
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Nov 1;12(21):6547-56
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Nov 1;12(21):6547-56
Survivin, a cancer target with an emerging role in normal adult tissues.
Fukuda S, Pelus LM
Molecular cancer therapeutics 2006 May;5(5):1087-98
Molecular cancer therapeutics 2006 May;5(5):1087-98
Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis.
Scase TJ, Edwards D, Miller J, Henley W, Smith K, Blunden A, Murphy S
Journal of veterinary internal medicine 2006 Jan-Feb;20(1):151-8
Journal of veterinary internal medicine 2006 Jan-Feb;20(1):151-8
Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis.
Scase TJ, Edwards D, Miller J, Henley W, Smith K, Blunden A, Murphy S
Journal of veterinary internal medicine 2006 Jan-Feb;20(1):151-8
Journal of veterinary internal medicine 2006 Jan-Feb;20(1):151-8
Expression of cytoplasmic and nuclear Survivin in primary and secondary human glioblastoma.
Xie D, Zeng YX, Wang HJ, Wen JM, Tao Y, Sham JS, Guan XY
British journal of cancer 2006 Jan 16;94(1):108-14
British journal of cancer 2006 Jan 16;94(1):108-14
TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo.
Kim EY, Priatel JJ, Teh SJ, Teh HS
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 15;176(2):1026-35
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 15;176(2):1026-35
TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo.
Kim EY, Priatel JJ, Teh SJ, Teh HS
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 15;176(2):1026-35
Journal of immunology (Baltimore, Md. : 1950) 2006 Jan 15;176(2):1026-35
Celecoxib decreases Ki-67 proliferative index in active smokers.
Mao JT, Fishbein MC, Adams B, Roth MD, Goodglick L, Hong L, Burdick M, Strieter ER, Holmes C, Tashkin DP, Dubinett SM
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Jan 1;12(1):314-20
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Jan 1;12(1):314-20
Angiotensin II and tumor necrosis factor-alpha upregulate survivin and Kruppel-like factor 5 in smooth muscle cells: Potential relevance to vein graft hyperplasia.
Bafford R, Sui XX, Wang G, Conte M
Surgery 2006 Aug;140(2):289-96
Surgery 2006 Aug;140(2):289-96
Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.
Kang BH, Altieri DC
The Journal of biological chemistry 2006 Aug 25;281(34):24721-7
The Journal of biological chemistry 2006 Aug 25;281(34):24721-7
Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation.
Pennati M, Campbell AJ, Curto M, Binda M, Cheng Y, Wang LZ, Curtin N, Golding BT, Griffin RJ, Hardcastle IR, Henderson A, Zaffaroni N, Newell DR
Molecular cancer therapeutics 2005 Sep;4(9):1328-37
Molecular cancer therapeutics 2005 Sep;4(9):1328-37
Adenoviral infection of survivin antisense sensitizes prostate cancer cells to etoposide in vivo.
Hayashi N, Asano K, Suzuki H, Yamamoto T, Tanigawa N, Egawa S, Manome Y
The Prostate 2005 Sep 15;65(1):10-9
The Prostate 2005 Sep 15;65(1):10-9
Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells.
Hata T, Yamamoto H, Ngan CY, Koi M, Takagi A, Damdinsuren B, Yasui M, Fujie Y, Matsuzaki T, Hemmi H, Xu X, Kitani K, Seki Y, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Monden M
Molecular cancer therapeutics 2005 Oct;4(10):1585-94
Molecular cancer therapeutics 2005 Oct;4(10):1585-94
Use of fuzzy neural networks in modeling relationships of HPV infection with apoptotic and proliferation markers in potentially malignant oral lesions.
Campisi G, Di Fede O, Giovannelli L, Capra G, Greco I, Calvino F, Maria Florena A, Lo Muzio L
Oral oncology 2005 Nov;41(10):994-1004
Oral oncology 2005 Nov;41(10):994-1004
Survivin inhibits anti-growth effect of p53 activated by aurora B.
Jung JE, Kim TK, Lee JS, Oh SY, Kwak S, Jin X, Sohn JY, Song MK, Sohn YW, Lee SY, Pian X, Lee JB, Chung YG, Choi YK, You S, Kim H
Biochemical and biophysical research communications 2005 Nov 4;336(4):1164-71
Biochemical and biophysical research communications 2005 Nov 4;336(4):1164-71
Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion.
Song J, So T, Cheng M, Tang X, Croft M
Immunity 2005 May;22(5):621-31
Immunity 2005 May;22(5):621-31
4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin.
Lubet RA, Huebner K, Fong LY, Altieri DC, Steele VE, Kopelovich L, Kavanaugh C, Juliana MM, Soong SJ, Grubbs CJ
Carcinogenesis 2005 Mar;26(3):571-8
Carcinogenesis 2005 Mar;26(3):571-8
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
McMurtry MS, Archer SL, Altieri DC, Bonnet S, Haromy A, Harry G, Bonnet S, Puttagunta L, Michelakis ED
The Journal of clinical investigation 2005 Jun;115(6):1479-91
The Journal of clinical investigation 2005 Jun;115(6):1479-91
Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1.
MacCallum DE, Melville J, Frame S, Watt K, Anderson S, Gianella-Borradori A, Lane DP, Green SR
Cancer research 2005 Jun 15;65(12):5399-407
Cancer research 2005 Jun 15;65(12):5399-407
Survivin expression predicts poorer prognosis in patients with areca quid chewing-related oral squamous cell carcinoma in Taiwan.
Lin CY, Hung HC, Kuo RC, Chiang CP, Kuo MY
Oral oncology 2005 Jul;41(6):645-54
Oral oncology 2005 Jul;41(6):645-54
A dopamine D4 receptor antagonist attenuates ischemia-induced neuronal cell damage via upregulation of neuronal apoptosis inhibitory protein.
Okada Y, Sakai H, Kohiki E, Suga E, Yanagisawa Y, Tanaka K, Hadano S, Osuga H, Ikeda JE
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005 Jul;25(7):794-806
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005 Jul;25(7):794-806
Expression of cell cycle markers and human papillomavirus infection in oral squamous cell carcinoma: use of fuzzy neural networks.
Lo Muzio L, D'Angelo M, Procaccini M, Bambini F, Calvino F, Florena AM, Franco V, Giovannelli L, Ammatuna P, Campisi G
International journal of cancer 2005 Jul 10;115(5):717-23
International journal of cancer 2005 Jul 10;115(5):717-23
A small C-terminal sequence of Aurora B is responsible for localization and function.
Scrittori L, Skoufias DA, Hans F, Gerson V, Sassone-Corsi P, Dimitrov S, Margolis RL
Molecular biology of the cell 2005 Jan;16(1):292-305
Molecular biology of the cell 2005 Jan;16(1):292-305
Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome.
Fangusaro JR, Jiang Y, Holloway MP, Caldas H, Singh V, Boué DR, Hayes J, Altura RA
British journal of cancer 2005 Jan 31;92(2):359-65
British journal of cancer 2005 Jan 31;92(2):359-65
Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.
Asanuma H, Torigoe T, Kamiguchi K, Hirohashi Y, Ohmura T, Hirata K, Sato M, Sato N
Cancer research 2005 Dec 1;65(23):11018-25
Cancer research 2005 Dec 1;65(23):11018-25
Survivin is a negative prognostic marker in medulloblastoma.
Pizem J, Cört A, Zadravec-Zaletel L, Popovic M
Neuropathology and applied neurobiology 2005 Aug;31(4):422-8
Neuropathology and applied neurobiology 2005 Aug;31(4):422-8
Cellular localisation of survivin: impact on the prognosis in colorectal cancer.
Ponnelle T, Chapusot C, Martin L, Bouvier AM, Plenchette S, Faivre J, Solary E, Piard F
Journal of cancer research and clinical oncology 2005 Aug;131(8):504-10
Journal of cancer research and clinical oncology 2005 Aug;131(8):504-10
A mutation found in the promoter region of the human survivin gene is correlated to overexpression of survivin in cancer cells.
Xu Y, Fang F, Ludewig G, Jones G, Jones D
DNA and cell biology 2004 Sep;23(9):527-37
DNA and cell biology 2004 Sep;23(9):527-37
Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms.
Chakravarti A, Zhai GG, Zhang M, Malhotra R, Latham DE, Delaney MA, Robe P, Nestler U, Song Q, Loeffler J
Oncogene 2004 Sep 30;23(45):7494-506
Oncogene 2004 Sep 30;23(45):7494-506
Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer.
Krysan K, Dalwadi H, Sharma S, Põld M, Dubinett S
Cancer research 2004 Sep 15;64(18):6359-62
Cancer research 2004 Sep 15;64(18):6359-62
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R
Cancer research 2004 Sep 1;64(17):6349-56
Cancer research 2004 Sep 1;64(17):6349-56
Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer.
Vischioni B, van der Valk P, Span SW, Kruyt FA, Rodriguez JA, Giaccone G
Annals of oncology : official journal of the European Society for Medical Oncology 2004 Nov;15(11):1654-60
Annals of oncology : official journal of the European Society for Medical Oncology 2004 Nov;15(11):1654-60
Cancer-specific activation of the survivin promoter and its potential use in gene therapy.
Chen JS, Liu JC, Shen L, Rau KM, Kuo HP, Li YM, Shi D, Lee YC, Chang KJ, Hung MC
Cancer gene therapy 2004 Nov;11(11):740-7
Cancer gene therapy 2004 Nov;11(11):740-7
Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes.
Ferrer A, Marcé S, Bellosillo B, Villamor N, Bosch F, López-Guillermo A, Espinet B, Solé F, Montserrat E, Campo E, Colomer D
Oncogene 2004 Nov 25;23(55):8941-9
Oncogene 2004 Nov 25;23(55):8941-9
Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma.
Schlette EJ, Medeiros LJ, Goy A, Lai R, Rassidakis GZ
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004 May 1;22(9):1682-8
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004 May 1;22(9):1682-8
Survivin enhances Fas ligand expression via up-regulation of specificity protein 1-mediated gene transcription in colon cancer cells.
Asanuma K, Tsuji N, Endoh T, Yagihashi A, Watanabe N
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3922-9
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3922-9
Survivin enhances Fas ligand expression via up-regulation of specificity protein 1-mediated gene transcription in colon cancer cells.
Asanuma K, Tsuji N, Endoh T, Yagihashi A, Watanabe N
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3922-9
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 15;172(6):3922-9
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression.
Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS
Journal of cell science 2004 Mar 15;117(Pt 8):1577-89
Journal of cell science 2004 Mar 15;117(Pt 8):1577-89
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle.
Gassmann R, Carvalho A, Henzing AJ, Ruchaud S, Hudson DF, Honda R, Nigg EA, Gerloff DL, Earnshaw WC
The Journal of cell biology 2004 Jul 19;166(2):179-91
The Journal of cell biology 2004 Jul 19;166(2):179-91
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.
Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R
Oncogene 2004 Jul 15;23(32):5426-34
Oncogene 2004 Jul 15;23(32):5426-34
COX-2-dependent stabilization of survivin in non-small cell lung cancer.
Krysan K, Merchant FH, Zhu L, Dohadwala M, Luo J, Lin Y, Heuze-Vourc'h N, Põld M, Seligson D, Chia D, Goodglick L, Wang H, Strieter R, Sharma S, Dubinett S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Jan;18(1):206-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Jan;18(1):206-8
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells.
Liu T, Brouha B, Grossman D
Oncogene 2004 Jan 8;23(1):39-48
Oncogene 2004 Jan 8;23(1):39-48
Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis.
Beltrami E, Plescia J, Wilkinson JC, Duckett CS, Altieri DC
The Journal of biological chemistry 2004 Jan 16;279(3):2077-84
The Journal of biological chemistry 2004 Jan 16;279(3):2077-84
Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray.
Zha H, Raffeld M, Charboneau L, Pittaluga S, Kwak LW, Petricoin E 3rd, Liotta LA, Jaffe ES
Laboratory investigation; a journal of technical methods and pathology 2004 Feb;84(2):235-44
Laboratory investigation; a journal of technical methods and pathology 2004 Feb;84(2):235-44
Survivin expression in ovarian carcinoma: correlation with apoptotic markers and prognosis.
Komuro Y, Watanabe T, Tsurita G, Muto T, Nagawa H
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004 Feb;17(2):264
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004 Feb;17(2):264
Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival.
Martinez A, Bellosillo B, Bosch F, Ferrer A, Marcé S, Villamor N, Ott G, Montserrat E, Campo E, Colomer D
The American journal of pathology 2004 Feb;164(2):501-10
The American journal of pathology 2004 Feb;164(2):501-10
IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression.
Kirkiles-Smith NC, Mahboubi K, Plescia J, McNiff JM, Karras J, Schechner JS, Altieri DC, Pober JS
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1391-6
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1391-6
IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression.
Kirkiles-Smith NC, Mahboubi K, Plescia J, McNiff JM, Karras J, Schechner JS, Altieri DC, Pober JS
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1391-6
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 1;172(3):1391-6
HPV DNA and survivin expression in epithelial oral carcinogenesis: a relationship?
Lo Muzio L, Campisi G, Giovannelli L, Ammatuna P, Greco I, Staibano S, Pannone G, De Rosa G, Di Liberto C, D'Angelo M
Oral oncology 2004 Aug;40(7):736-41
Oral oncology 2004 Aug;40(7):736-41
Megakaryocytes express functional Aurora-B kinase in endomitosis.
Geddis AE, Kaushansky K
Blood 2004 Aug 15;104(4):1017-24
Blood 2004 Aug 15;104(4):1017-24
Roles of iNOS and nNOS in sepsis-induced pulmonary apoptosis.
Rudkowski JC, Barreiro E, Harfouche R, Goldberg P, Kishta O, D'Orleans-Juste P, Labonte J, Lesur O, Hussain SN
American journal of physiology. Lung cellular and molecular physiology 2004 Apr;286(4):L793-800
American journal of physiology. Lung cellular and molecular physiology 2004 Apr;286(4):L793-800
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis.
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA
The Journal of cell biology 2003 Sep 1;162(5):863-75
The Journal of cell biology 2003 Sep 1;162(5):863-75
A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis.
Zhao Z, Ho L, Suh J, Qin W, Pyo H, Pompl P, Ksiezak-Reding H, Pasinetti GM
Molecular and cellular neurosciences 2003 Oct;24(2):367-79
Molecular and cellular neurosciences 2003 Oct;24(2):367-79
A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis.
Zhao Z, Ho L, Suh J, Qin W, Pyo H, Pompl P, Ksiezak-Reding H, Pasinetti GM
Molecular and cellular neurosciences 2003 Oct;24(2):367-79
Molecular and cellular neurosciences 2003 Oct;24(2):367-79
Nuclear expression of Survivin in paediatric ependymomas and choroid plexus tumours correlates with morphologic tumour grade.
Altura RA, Olshefski RS, Jiang Y, Boué DR
British journal of cancer 2003 Nov 3;89(9):1743-9
British journal of cancer 2003 Nov 3;89(9):1743-9
Regulation of survivin function by Hsp90.
Fortugno P, Beltrami E, Plescia J, Fontana J, Pradhan D, Marchisio PC, Sessa WC, Altieri DC
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):13791-6
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):13791-6
Gene expression and mitotic exit induced by microtubule-stabilizing drugs.
Chen JG, Yang CP, Cammer M, Horwitz SB
Cancer research 2003 Nov 15;63(22):7891-9
Cancer research 2003 Nov 15;63(22):7891-9
Characterization of antigen processing machinery and Survivin expression in tonsillar squamous cell carcinoma.
Weinman EC, Roche PC, Kasperbauer JL, Cha SS, Sargent DJ, Cheville J, Murphy LM, Chen L, Wettstein PJ, Gostout B, Ferrone S, Strome SE
Cancer 2003 May 1;97(9):2203-11
Cancer 2003 May 1;97(9):2203-11
Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.
Ramp U, Caliskan E, Mahotka C, Krieg A, Heikaus S, Gabbert HE, Gerharz CD
British journal of cancer 2003 Jun 2;88(11):1800-7
British journal of cancer 2003 Jun 2;88(11):1800-7
Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis.
Blanc-Brude OP, Mesri M, Wall NR, Plescia J, Dohi T, Altieri DC
Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Jul;9(7):2683-92
Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Jul;9(7):2683-92
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.
Carvalho A, Carmena M, Sambade C, Earnshaw WC, Wheatley SP
Journal of cell science 2003 Jul 15;116(Pt 14):2987-98
Journal of cell science 2003 Jul 15;116(Pt 14):2987-98
Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces antiapoptotic and proapoptotic signals in acute myeloid leukemia.
Faderl S, Harris D, Van Q, Kantarjian HM, Talpaz M, Estrov Z
Blood 2003 Jul 15;102(2):630-7
Blood 2003 Jul 15;102(2):630-7
Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma.
Grabowski P, Kühnel T, Mühr-Wilkenshoff F, Heine B, Stein H, Höpfner M, Germer CT, Scherübl H
British journal of cancer 2003 Jan 13;88(1):115-9
British journal of cancer 2003 Jan 13;88(1):115-9
Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells.
Miranda MB, Dyer KF, Grandis JR, Johnson DE
Leukemia 2003 Feb;17(2):390-400
Leukemia 2003 Feb;17(2):390-400
Survivin expression in oral squamous cell carcinoma.
Lo Muzio L, Pannone G, Staibano S, Mignogna MD, Rubini C, Mariggiò MA, Procaccini M, Ferrari F, De Rosa G, Altieri DC
British journal of cancer 2003 Dec 15;89(12):2244-8
British journal of cancer 2003 Dec 15;89(12):2244-8
Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway.
Fornaro M, Plescia J, Chheang S, Tallini G, Zhu YM, King M, Altieri DC, Languino LR
The Journal of biological chemistry 2003 Dec 12;278(50):50402-11
The Journal of biological chemistry 2003 Dec 12;278(50):50402-11
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.
Honda R, Körner R, Nigg EA
Molecular biology of the cell 2003 Aug;14(8):3325-41
Molecular biology of the cell 2003 Aug;14(8):3325-41
Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
Chen Y, Kramer DL, Li F, Porter CW
Oncogene 2003 Aug 7;22(32):4964-72
Oncogene 2003 Aug 7;22(32):4964-72
Prognostic importance of survivin in breast cancer.
Kennedy SM, O'Driscoll L, Purcell R, Fitz-Simons N, McDermott EW, Hill AD, O'Higgins NJ, Parkinson M, Linehan R, Clynes M
British journal of cancer 2003 Apr 7;88(7):1077-83
British journal of cancer 2003 Apr 7;88(7):1077-83
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, Heckel A, van Meel J, Rieder CL, Peters JM
The Journal of cell biology 2003 Apr 28;161(2):281-94
The Journal of cell biology 2003 Apr 28;161(2):281-94
Inhibitor of apoptosis protein survivin regulates vascular injury.
Blanc-Brude OP, Yu J, Simosa H, Conte MS, Sessa WC, Altieri DC
Nature medicine 2002 Sep;8(9):987-94
Nature medicine 2002 Sep;8(9):987-94
Induction of apoptosis by bexarotene in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action.
Zhang C, Hazarika P, Ni X, Weidner DA, Duvic M
Clinical cancer research : an official journal of the American Association for Cancer Research 2002 May;8(5):1234-40
Clinical cancer research : an official journal of the American Association for Cancer Research 2002 May;8(5):1234-40
Regulation of microtubule stability and mitotic progression by survivin.
Giodini A, Kallio MJ, Wall NR, Gorbsky GJ, Tognin S, Marchisio PC, Symons M, Altieri DC
Cancer research 2002 May 1;62(9):2462-7
Cancer research 2002 May 1;62(9):2462-7
2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells.
Qanungo S, Basu A, Das M, Haldar S
Oncogene 2002 Jun 13;21(26):4149-57
Oncogene 2002 Jun 13;21(26):4149-57
A p34(cdc2) survival checkpoint in cancer.
O'Connor DS, Wall NR, Porter AC, Altieri DC
Cancer cell 2002 Jul;2(1):43-54
Cancer cell 2002 Jul;2(1):43-54
A p34(cdc2) survival checkpoint in cancer.
O'Connor DS, Wall NR, Porter AC, Altieri DC
Cancer cell 2002 Jul;2(1):43-54
Cancer cell 2002 Jul;2(1):43-54
Increased expression of survivin in gastric cancer patients and in first degree relatives.
Yu J, Leung WK, Ebert MP, Ng EK, Go MY, Wang HB, Chung SC, Malfertheiner P, Sung JJ
British journal of cancer 2002 Jul 1;87(1):91-7
British journal of cancer 2002 Jul 1;87(1):91-7
Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas.
Mahotka C, Krieg T, Krieg A, Wenzel M, Suschek CV, Heydthausen M, Gabbert HE, Gerharz CD
International journal of cancer 2002 Jul 1;100(1):30-6
International journal of cancer 2002 Jul 1;100(1):30-6
Quantitatively determined survivin expression levels are of prognostic value in human gliomas.
Chakravarti A, Noll E, Black PM, Finkelstein DF, Finkelstein DM, Dyson NJ, Loeffler JS
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002 Feb 15;20(4):1063-8
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002 Feb 15;20(4):1063-8
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.
Fortugno P, Wall NR, Giodini A, O'Connor DS, Plescia J, Padgett KM, Tognin S, Marchisio PC, Altieri DC
Journal of cell science 2002 Feb 1;115(Pt 3):575-85
Journal of cell science 2002 Feb 1;115(Pt 3):575-85
Differential subcellular localization of functionally divergent survivin splice variants.
Mahotka C, Liebmann J, Wenzel M, Suschek CV, Schmitt M, Gabbert HE, Gerharz CD
Cell death and differentiation 2002 Dec;9(12):1334-42
Cell death and differentiation 2002 Dec;9(12):1334-42
Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning.
Zhu L, Fukuda S, Cordis G, Das DK, Maulik N
FEBS letters 2001 Nov 23;508(3):369-74
FEBS letters 2001 Nov 23;508(3):369-74
Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning.
Zhu L, Fukuda S, Cordis G, Das DK, Maulik N
FEBS letters 2001 Nov 23;508(3):369-74
FEBS letters 2001 Nov 23;508(3):369-74
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.
Wheatley SP, Carvalho A, Vagnarelli P, Earnshaw WC
Current biology : CB 2001 Jun 5;11(11):886-90
Current biology : CB 2001 Jun 5;11(11):886-90
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.
Wheatley SP, Carvalho A, Vagnarelli P, Earnshaw WC
Current biology : CB 2001 Jun 5;11(11):886-90
Current biology : CB 2001 Jun 5;11(11):886-90
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis.
Zeitlin SG, Shelby RD, Sullivan KF
The Journal of cell biology 2001 Dec 24;155(7):1147-57
The Journal of cell biology 2001 Dec 24;155(7):1147-57
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Supportive validation
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- Simple Western: Survivin Antibody [NB500-201] - Simple Western analysis using [NB500-201]. Lane view shows a specific band for Survivin in 1.0 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Theoretical molecular weight: 16 kDa.
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- Western Blot: Survivin Antibody [NB500-201] - Analysis of Survivin in human hepatocytes from cancer patient (left) and HeLa cell lysate (right) using [NB500-201]. Image from verified customer review. Note: bands detected at higher molecular weight than predicted (16 kDa)
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- Western Blot: Survivin Antibody [NB500-201] - Analysis of 30ug of HeLa whole cell lysate [NB800-PC1] using rabbit polyclonal [NB500-201] at 1ug/ml. Detection was performed using ECL method with 1 minute exposure. Band detected at higher molecular weight than the predicted MW (16 kDa).
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- Western Blot: Survivin Antibody [NB500-201] - Analysis of Survivin in HeLa cell lysate. Image courtesy of anonymous customer review.
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- Western Blot: Survivin Antibody [NB500-201] - Analysis shows lysates of human neuroblastoma cell line. PVDF membrane was probed with 1:200 dilution of 0.5 ug/mL of rabbit anti-Survivin polyclonal (NB500-201, Novus Biologicals), followed by 1:2000 dilution of goat anti-rabbit IgG.
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- Western Blot: Survivin Antibody [NB500-201] - Whole cell extracts were prepared in RIPA buffer and analyzed using immunoblot analysis. PVDF membrane. Primary antibody 1:1000 at 4C overnight. Secondary antibody 1:20000 at 4C for 1 hour. This image was submitted via customer Review.
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- Western Blot: Survivin Antibody [NB500-201] - Western blot analysis using Survivin Antibody [NB500-201]. Effects of siRNA transfection on the expression of Bcl-xL and survivin. Bcl-xL and survivin protein content detected by Western Blotting 48 h after transfection. Bcl-xL and survivin levels are shown normalized to the reference protein beta-actin and relative to the ns-si control. Image collected and cropped by CiteAb from the following publication (http://www.mdpi.com/1422-0067/14/6/12297) licensed under a CC-BY licence.
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- Western Blot: Survivin Antibody [NB500-201] - Western blot analysis using [NB500-201]. Survivin protein is degraded by ubiquitin proteasome in serum-free and serum-containing media. Western blots and protein quantitation graphs showing that addition of MG-132 proteasome inhibitor (10 uM) extended survivin protein half-life in serum-free and serum-containing media. One representative western blot out of triplicate experiments was shown for each treatment and condition. *Indicates the time at which survivin protein is half of the amount at 0 hours (half-life), P < 0.02. Image collected and cropped by CiteAb from the following publication (http://www.hindawi.com/journals/grp/2012/897678/) licensed under a CC-BY licence.
Supportive validation
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- Immunohistochemistry-Paraffin: Survivin Antibody [NB500-201] - Immunohistochemical staining of Survivin in human rectal cancer using [NB500-201] and DAB with hematoxylin counterstain.
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- Immunohistochemistry-Paraffin: Survivin Antibody [NB500-201] - Analysis of Survivin in ovarian cancer tissue using [NB500-201]. Image from verified customer review.
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- Immunohistochemistry: Survivin Antibody [NB500-201] - Immunohistochemical analysis using [NB500-201]. The top photo is a control stain and the bottom photo is anti-survivin staining of melanoma. Photo courtesy of Dr. Dario Altieri, Yale University.
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- Immunohistochemistry: Survivin Antibody [NB500-201] - HRP conjugated Survivin expression in BIRC5 transfected 293T cells using Survivin Antibody [NB500-201]. Image from verified customer review.
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- Immunohistochemistry-Paraffin: Survivin Antibody [NB500-201] - Survivin shows lysates of human neuroblastoma cell line. Polyvinylidene fluoride (PVDF) membrane was probed with 1:200 dilution of 0.5 ug/mL of rabbit polyclonal Survivin Antibody [NB500-201], followed by 1:2000 dilution of goat anti-rabbit IgG.
Supportive validation
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- Flow Cytometry: Survivin Antibody [NB500-201] - An intracellular stain was performed on HeLa cells with [NB500-201] and a matched isotype control. Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature, followed by Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Dylight 550.
