MAB1597

antibody from R&D Systems

Targeting: FCGR3B CD16, CD16b, FCG3, FCGR3

Western blot (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB1597

Provider

R&D Systems

Product name

Human Fc gamma RIIIB/CD16b Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Fc gamma RIIIB/CD16b in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human Fc gamma RIIA or recombinant mouse Fc gamma RIII is observed. In flow cytometry of whole blood, recognition of Fc gamma RIIIB on the granulocyte population, but not Fc gamma RIIIA on NK cells, is observed.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

O75015


Isotype

IgG

Antibody clone number

245514

Vial size

500 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes.

Ceeraz S, Eszterhas SK, Sergent PA, Armstrong DA, Ashare A, Broughton T, Wang L, Pechenick D, Burns CM, Noelle RJ, Vincenti MP, Fava RA
Arthritis research & therapy 2017 Dec 8;19(1):270

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α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8.

Bergin DA, Reeves EP, Meleady P, Henry M, McElvaney OJ, Carroll TP, Condron C, Chotirmall SH, Clynes M, O'Neill SJ, McElvaney NG
The Journal of clinical investigation 2010 Dec;120(12):4236-50