BS60034

antibody from Bioworld Technology, Inc
Targeting: LSM1 CASM, YJL124C
Provider product page for BS60034

Antibody data

Product number
BS60034 - Provider product page
Provider
Bioworld Technology, Inc
Product name
LSM1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human LSM1.
Description
Sm and Sm-like (LSm) proteins form donut-shaped heptameric complexes that are involved in various steps of RNA metabolism. LSm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm1, also designated U6 snRNA-associated Sm-like protein or small nuclear ribonuclear CaSm, binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm1 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1/2 and the exonuclease Xm1. LSm1 is naturally overexpressed in pancreatic cancer as well as in certain breast cancer cell lines. The downregulation of LSm1 is involved in the progression of prostate cancer.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
LSM1 protein structure - BS60034 shown in red.