Antibody data

Product number
orb76162
Provider
Biorbyt
Product name
MAOA antibody
Provider product page
Biorbyt - orb76162
Antibody type
Polyclonal
Description
Rabbit Polyclonal to MAOA. MAOA(Monoamine oxidase A), also known as AMINE OXIDASE (FLAVIN-CONTAINING) A, is an enzyme that in humans is encoded by the MAO-A gene.MAOA is an isozyme of monoamine oxidase which is also mapped on Xp11.3.MAOA degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Mutation in MAOA results in monoamine oxidase deficiency, or Brunner syndrome. In humans, there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Inhibition of MAOA prevented apoptosis, and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Vial size
100 μg
Concentration
0.1-0.5 μg/ml,0.5-1 μg/ml
Storage
Store at -20°C for one year.After reconstitution, at 4°C. for one month. It can also be aliquotted and stored frozen at -20°C. for a longer time.Avoid repeated freezing and thawing.
Provider Type Product Number
- No reagents -