BS8769

antibody from Bioworld Technology, Inc
Targeting: MCM10 CNA43, DNA43, PRO2249
Provider product page for BS8769
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8769 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MCM10 polyclonal antibody
Antibody type
Polyclonal
Antigen
Protein MCM10 homolog; HsMCM10; MCM10; PRO2249
Description
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MCM10 protein structure - BS8769 shown in red.