orb99186

antibody from Biorbyt

Targeting: EIF2AK1 HRI, KIAA1369

Immunohistochemistry

Antibody data

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Validation data

Product number: orb99186 - Provider product page
Provider: Biorbyt
Product name: EIF2AK1 antibody
Antibody type: Polyclonal
Description: Rabbit Polyclonal to EIF2AK1. EIF2AK1 (Eukaryotic Translation Initiation Factor 2-Alpha Kinase 1), also called HRI, is an enzyme that in humans is encoded by the EIF2AK1 gene. Hartz (2010) mapped the EIF2AK1 gene to chromosome 7p22.1 based on an alignment of the EIF2AK1 sequence with the genomic sequence. Chen and London (1995) reviewed the activation and control of rat and rabbit Hri. Hri functions as a dimer, and its activation involves autophosphorylation, which requires an invariant lysine in kinase domain II. Using cDNA arrays and Northern blot analysis, Hwang et al. (2000) found that HRI was downregulated in the majority of ovarian cancers examined compared with normal ovarian tissues.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Vial size: 100 μg
Concentration: 500μg/ml
Storage: Store at -20°C for one year.After reconstitution, at 4°C. for one month. It can also be aliquotted and stored frozen at -20°C. for a longer time. Avoid repeated freezing and thawing.

EIF2AK1 protein structure - orb99186 shown in red.