339919

antibody from BioLegend

Targeting: KLRB1 CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A

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Antibody data

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Validation data

Product number: 339919 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#339919, RRID:AB_2562836
Product name: Purified anti-human CD161 (MaxPar® Ready)
Antibody type: Monoclonal
Antigen: Human NK cells
Description: CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3⁺ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4⁺CD161⁺CCR6⁺ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antibody clone number: HP-3G10
Vial size: 100 µg
Concentration: 1 mg/ml
Storage: 2°C-8°C
Handling: Ambient RT

KLRB1 protein structure - 339919 shown in red.