45-1619-41

antibody from Invitrogen Antibodies
Targeting: KLRB1 CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A
Provider product page for 45-1619-41

Antibody data

Product number
45-1619-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD161 Monoclonal Antibody (HP-3G10), PerCP-Cyanine5.5, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This HP-3G10 monoclonal antibody reacts with CD161 (also known as NKR-P1A), a member of the C-type lectin superfamily. The human homologue of NK1.1 in C57BL/6 mice, CD161 is expressed on natural killer cells and is upregulated in response to IL-12. CD161 can also be detected on various T cell subsets, including memory/effector CD4+ T cells, CD8+ T cells, gammadeltaTCR T cells, and a subset of CD3+ thymocytes. Finally, CD161 expression has been demonstrated on human Th17 CD4+ T cells. The function of this receptor is unclear although studies suggest a possible stimulatory role. Nevertheless, Lectin-like transcript-1 (LLT1), which is also known as osteoclast inhibitory lectin, has been identified as the ligand for CD161. Applications Reported: This HP-3G10 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HP-3G10 antibody has been pre-titrated and tested by flow cytometric analysis on normal human peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
HP-3G10
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
KLRB1 protein structure - 45-1619-41 shown in red.