CABT-B12191

antibody from Creative Diagnostics

Targeting: PTPRJ CD148, DEP1, HPTPeta

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12191

Provider

Creative Diagnostics

Product name

Human anti-Human PTPRJ recombinant monoclonal antibody, clone SFB305 [FITC]

Antibody type

Monoclonal

Description

It recognozes CD148, a receptor type protein tyrosine phosphatase (PTP) belonging to the type III family of PTPs. CD148 is characterized by an extracellular domain with eight fibronectin type III repeats, a trans-membrane region, and a single cytosolic catalytic domain. Expression of CD148 is found on mature thymocytes, peripheral T cells, B cells, NK cells, granulocytes, macrophages, DC subpopulations, epithelial and endothelial cells, and fibroblasts. An upregulated expression of CD148 on human peripheral T cells is observed upon TCR stimulation. CD148 via regulating the phosphorylation status of substrates such as PDGFR, p120 catenin (CTND1), and SRC kinase, plays vital role in many cellular functions. Additional information: It displays negligible binding to Fc receptors.

Reactivity

Human

Host

Human

Conjugate

Green dye

Isotype

IgG

Antibody clone number

SFB305

Vial size

for 100 tests

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.