MAB1058

antibody from R&D Systems

Targeting: KLRD1 CD94

Flow cytometry (Data presented on provider website)

Blocking/Neutralizing (Data presented on provider website)

Antibody Data

Product number

MAB1058

Provider

R&D Systems

Product name

Human CD94 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Recognizes human CD94 both in its homodimeric form and as a heterodimer with either NKG2A or NKG2C.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

131412

Vial size

500 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

MicroRNA editing facilitates immune elimination of HCMV infected cells.

Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le VT, Galun E, Horejsi V, Isakov O, Shomron N, Wolf DG, Hengel H, Mandelboim O
PLoS pathogens 2014 Feb;10(2):e1003963

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NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.

Angelini DF, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, Poccia F, Semenzato G, Borsellino G, Santoni A, Battistini L
Journal of leukocyte biology 2011 Jan;89(1):75-84

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CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets.

Yu J, Mao HC, Wei M, Hughes T, Zhang J, Park IK, Liu S, McClory S, Marcucci G, Trotta R, Caligiuri MA
Blood 2010 Jan 14;115(2):274-81