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Cell line expression
Protein structure
GPNMB
Glycoprotein nmbHGFIN, NMB
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| R&D Systems |  AF2550 |
12 references | Polyclonal |
WB
EL
IHC
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| Proteintech Group | 20338-1-AP |
4 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN1724859 |
2 references | Monoclonal |
WB
EL
IHC
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| Boster Biological Technology | A02439-1 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Invitrogen Antibodies | MA5-24014 |
1 references | Monoclonal |
ICC
FC
OA
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