Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MAB0059 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB0059, RRID:AB_1017058
- Product name
- ARHGDIB monoclonal antibody, clone 97A1015
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of ARHGDIB.
- Isotype
- IgG
- Antibody clone number
- 97A1015
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Pseudomonas aeruginosa-induced human mast cell apoptosis is associated with up-regulation of endogenous Bcl-xS and down-regulation of Bcl-xL.
Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism.
Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis.
Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species.
Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids.
Jenkins CE, Swiatoniowski A, Power MR, Lin TJ
Journal of immunology (Baltimore, Md. : 1950) 2006 Dec 1;177(11):8000-7
Journal of immunology (Baltimore, Md. : 1950) 2006 Dec 1;177(11):8000-7
Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism.
Jenkins CE, Swiatoniowski A, Issekutz AC, Lin TJ
The Journal of biological chemistry 2004 Aug 27;279(35):37201-7
The Journal of biological chemistry 2004 Aug 27;279(35):37201-7
Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis.
Liu CY, Lee CF, Hong CH, Wei YH
Annals of the New York Academy of Sciences 2004 Apr;1011:133-45
Annals of the New York Academy of Sciences 2004 Apr;1011:133-45
Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species.
Ko CH, Shen SC, Chen YC
Free radical biology & medicine 2004 Apr 1;36(7):897-910
Free radical biology & medicine 2004 Apr 1;36(7):897-910
Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids.
Chen YC, Shen SC, Lin HY
Biochemical pharmacology 2003 Oct 1;66(7):1139-50
Biochemical pharmacology 2003 Oct 1;66(7):1139-50
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of ARHGDIB in Jurkat cells using ARHGDIB monoclonal antibody, clone 10D774 (Cat # MAB0058) at 2 ug/mL and ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) at 0.1 ug/mL. Cells were treated with 2 uM staurosporine for different time periods. ARHGDIB monoclonal antibody, clone 10D774 (Cat # MAB0058) detects both the full-length and cleaved forms of ARHGDIB while ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) specifically detects only the cleaved form of the protein.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) in formalin-fixed, paraffin-embedded human breast tumor tissue using an isotype control (top) and ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) (bottom) at 5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
