BS8264

antibody from Bioworld Technology, Inc

Targeting: PRDM14

Western blot (Data presented on provider website)

Antibody Data

Product number

BS8264

Provider

Bioworld Technology, Inc

Product name

PRDM14 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human PRDM14.

Description

The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, called PR-plus and PR-minus, which differ by the presence or absence of the PR domain, respectively. The PR-plus product is underexpressed or disrupted in cancer cells, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining factor of malignancy. PRDM14 (PR domain-containing protein 14), also known as PFM11, is a 571 amino acid protein belonging to the PRDM family. Localizing to the nucleus, PRDM14 contains six C2H2-type zinc fingers and one SET domain. It is believed to participate in transcriptional regulation and may be involved in cell differentiation and tumorigenesis.

Reactivity

Mouse

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.