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Cell line expression
Protein structure
CASP3
Caspase 3apopain, CPP32, CPP32B, Yama
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| Proteintech Group |  19677-1-AP |
1147 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 700182 |
21 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| GeneTex | GTX110543 |
54 references | Polyclonal |
WB
ICC
IP
IHC
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| antibodies-online | ABIN252651 |
110 references | Monoclonal |
WB
ICC
IHC
FC
IEM
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| R&D Systems | MAB835 |
40 references | Monoclonal |
WB
ICC
IHC
FC
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